Browsing by Author "Miranda, M."

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    Autoimmune thyroid disease in the puerperium. Predictive value of thyroid enlargement and related hormonal changes occurring during pregnancy
    (1990) Fardella B., Carlos; Lopez, J. M.; Valdés, M. E.; Nuñez, M.; Miranda, M.
    The incidence of goiter detected during pregnancy and its significance as an indicator of autoimmune thyroid disease after delivery was investigated in a sample of 707 pregnant women (81% in their 2ndtrimester of gestation). Goiter was detected in 106 subjects (15%). Blood T4, T3, TSH, free T4 index (FT4I), antimicrosomal antibodies (AMA) and urinary iodine excretion were measured in these women and in a control group of gravidas without goiter. These measurements were repeated at 1 and 3 months after delivery. Compared with controls during pregnancy, subjects with goiter had lower FT4I values (11.0 2.8 vs 9.0 1.8; p < 0.01) and higher TSH values (2.9 0.6 ?U/ml vs 4.2 2.1 ?U/ml; p < 0.01). In contrast, T4, T3, AMA and urinary iodine excretion values were similar in both groups. In subjects with goiter FT4I values increased over pregnancy levels at 1 month (11.2 2.0; p < 0.05) and 3 months (14.0 3.0; p < 0.05) after delivery; in 29% a biochemical hyperthyroidism (FT4I > 13.5) was detected. During the same period TSH values decreased significantly (1 month: 1.9 0.7 ?U/ml; p < 0.05; 3 months: 2.7 3.0 ?U/ml; p < 0.05). Frequency of positive AMA increased from 8.6% during pregnancy up to 32.1% in the post-delivery period (p < 0.01). In the control group no variation in the FT4I, TSH or AMA were observed after delivery. These results indicate that goiter during pregnancy is common in Chilean gravidas and that it has predictive value for the appearance of autoimmune thyroid disease after delivery.
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    Landscape Analysis of Adult Codling Moth (Lepidoptera: Tortricidae) Distribution and Dispersal Within Typical Agroecosystems Dominated by Apple Production in Central Chile
    (OXFORD UNIV PRESS INC, 2010) Basoalto, E.; Miranda, M.; Knight, A. L.; Fuentes Contreras, E.
    We analyzed the spatial distribution and dispersal of codling moth, Cydia pomonella (L.), adults within two heterogeneous agroecosystems typical of central Chile: commercial apple, Malus domestica Borkhausen, orchards surrounded by various unmanaged host plants. Both a geostatistical analysis of catches of adult males with a grid of sex pheromone-baited traps and an immunological self-marking technique combined with traps baited with a male and female attractant were used. The spatial analyses identified the key sources of moths within these diverse landscapes. Codling moth catches in traps were spatially associated within distances of approximate to 150-300 m. Similarly, the mean distance from the immunological self-marking plots within the commercial apple orchard to the traps that captured marked adults was 282 m. In contrast, the mean distance in the capture of marked moths from unmanaged self-marking plots to a commercial orchard was 828 m. These data suggest that the success of any future areawide management programs for codling moth in Chilean pome fruit must include a component for managing or removing noncommercial hosts that surround orchards. This analysis also suggests that the selection pressure for resistance imposed by insecticide sprays within managed orchards is likely dampened by the influx of susceptible moths from unmanaged sites common in central Chile.
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    Life-threatening risk of using Kambo in alternative medicine
    (2020) Álamos Grau, María Florencia; Walker, R. H.; Miranda, M.
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    Myocardial Monophasic Action Potential Recorded by Suction Electrode for Ionic Current Studies in Zebrafish
    (2019) Miranda, M.; Egaña, José T.; Allende, M.L.; Eblen Zajjur, Antonio Alejandro