Browsing by Author "Martinez, P."

Now showing 1 - 6 of 6
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    Epidemiological, clinical and biochemical characterization of the p.(Ala359Asp) SMPD1 variant causing Niemann-Pick disease type B
    (2016) Acuna, M.; Martinez, P.; Moraga, C.; He, X.; Moraga, M.; Hunter, B.; Nuernberg, P.; Gutiérrez Ilabaca, Rodrigo Antonio; Gonzalez, M.; Schuchman, E.; Santos Martín, José Luis; Miquel P., Juan Francisco; Mabe, P.; Zanlungo Matsuhiro, Silvana
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    Fast skeletal myofibers of mdx mouse, model of Duchenne muscular dystrophy, express connexin hemichannels that lead to apoptosis
    (2016) Cea, L.; Puebla Aracena, Carlos Alberto; Cisterna Irrazabal, Bruno Alejandro; Escamilla, R.; Vargas, A.; Frank, M.; Martinez, P.; Prior, C.; Molano, J.; Esteban, I.; Pascual, I.; Gallano, P.; Lorenzo, G.; Pian, H.; Barrio, L.; Willecke, K.; Sáez, Juan Carlos
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    Helicobacter pylori vacA s1a and s1b alleles from clinical isolates from different regions of Chile show a distinct geographic distribution
    (BAISHIDENG PUBLISHING GROUP INC, 2005) Diaz, M. I.; Valdivia, A.; Martinez, P.; Palacios, J. L.; Harris, P.; Novales, J.; Garrido, E.; Valderrama, D.; Shilling, C.; Kirberg, A.; Hebel, E.; Fierro, J.; Bravo, R.; Siegel, F.; Leon, G.; Klapp, G.; Venegas, A.
    AIM: To establish the most common vacA alleles in Helicobacter pylori (H pylori) strains isolated from Chilean patients and its relationship with gastritis and gastroduodenal ulcers.
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    Hepatic metabolic response to restricted copper intake in a Niemann-Pick C murine model
    (2014) Argueello, G.; Martinez, P.; Peña, J.; Chen, O.; Platt, F.; Zanlungo Matsuhiro, Silvana; González, M.
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    Internet-Based Interventions for the Prevention and Treatment of Mental Disorders in Latin America : A Scoping Review
    (2019) Jimenez-Molina, A.; Franco Vivanco, Pamela Verónica; Martinez, V.; Martinez, P.; Rojas, G.; Araya, R.
    Background: There is a huge gap in the treatment of mental disorders in Latin America, especially among socioeconomically disadvantaged groups. Given the sharp increase in Internet access and the rapid penetration of smartphones in the region, the use of Internet-based technologies might potentially contribute to overcoming this gap and to provide more widely distributed and low-cost mental health care in a variety of contexts. Methods: We conducted a scoping review of the literature in order to systematically map the existing evidence on use of Internet-based interventions for prevention, treatment, and management of mental disorders across Latin American countries, as well as to identify existing gaps in knowledge. Six electronic databases were searched for published papers (PubMed, Embase, CINAHL, Web of Science, SciELO, and CENTRAL). Results: After the eligibility assessment, we identified 22 Internet-based studies carried out in Latin America for prevention, treatment, education, or facilitating self-management of mental disorders. Included studies mainly targeted depression (n = 11), substance misuse (n = 6), anxiety (n = 3), and mental health literacy for education and health professionals (n = 2). Most studies were undertaken in Brazil (n = 6), Mexico (n = 5), and Chile (n = 4). Only 3 studies were randomized controlled trials (RCTs), 4 were pilot RCTs, and 15 were naturalistic, acceptability, or feasibility studies. The three RCTs identified showed disparate results, but overall, there are challenges to face. Better results are seen in the short-term (postintervention or after 3 months), but most studies do not explore outcomes for long enough (follow-up after 6 or 12 months). Most of the feasibility and pilot studies showed reasonably good acceptability for a wide range of strategies but difficulties to engage and retain participants for long enough or adhering to established protocols. Conclusion: This study shows that Internet-based interventions for the prevention and treatment of mental disorders are growing rapidly in Latin America, but there are few studies on effectiveness and cost effectiveness, making it difficult to provide the evidence needed to justify scaling up these interventions.
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    Massive volume fly-ash concrete : a more sustainable material with fly ash replacing cement and aggregates
    (2015) Rivera, F.; Martinez, P.; Castro, J.; López Casanova, Mauricio Alejandro