Browsing by Author "Lopez, Maria Victorina"

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    Chronic obstructive pulmonary disease and body mass index in five Latin America cities: The PLATINO study
    (W B SAUNDERS CO LTD, 2008) de Oca, Maria Montes; Talamo, Carlos; Perez Padilla, Rogelio; Jardim, Jose Roberto B.; Muino, Adriana; Lopez, Maria Victorina; Valdivia, Gonzalo; Pertuze, Julio; Moreno, Dolores; Halbert, Ronald J.; Menezes, Ana Maria B.; Platino Team
    Background: The body mass index (BMI) is a prognostic factor for chronic obstructive pulmonary disease (COPD). Despite its importance, little information is available regarding BMI alteration in COPD from a population-based study. We examined characteristics by BMI categories in the total and COPD populations in five Latin-American cities, and explored the factors influencing BMI in COPD.
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    Diagnostic Labeling of COPD in five Latin American cities
    (ELSEVIER, 2007) Talamo, Carlos; Montes de Oca, Maria; Halbert, Ron; Perez Padilla, Rogelio; Jardim, Jose Roberto B.; Muino, Adriana; Lopez, Maria Victorina; Valdivia, Gonzalo; Pertuze, Julio; Moreno, Dolores; Menezes, Ana Maria B.; PLATINO Team
    Background: COPD is a major worldwide problem with a rising prevalence. Despite its importance, there is a lack of information regarding underdiagnosis and misdiagnosis of COPD in different countries. As part of the Proyecto Latinoamericano de Investigacion en Obstruccion Pulmonar study, we examined the relationship between prior diagnostic label and airway obstruction in the metropolitan areas of five Latin American cities (S (a) over tildeo Paulo, Santiago, Mexico City, Montevideo, and Caracas).
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    Outcomes for symptomatic non-obstructed individuals and individuals with mild (GOLD stage I) COPD in a population based cohort
    (2018) Perez-Padilla, Rogelio; Wehrmeister, Fernando C.; Montes de Oca, María; Lopez, Maria Victorina; Jardim, Jose R.; Muiño A.; Valdivia Cabrera, Gonzalo; Menezes A.M.B.
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    Spirometric reference values in 5 large Latin American cities for subjects aged 40 years or over
    (ELSEVIER ESPANA SLU, 2006) Perez Padilla, Rogelio; Valdivia, Gonzalo; Muino, Adriana; Lopez, Maria Victorina; Marquez, Maria Nelly; de Oca, Maria Montes; Talamo, Carlos; Lisboa, Carmen; Pertuze, Julio; Jardim, Jose Roberto B.; Menezes, Ana Maria B.; Grp Trabajo PLATINO
    OBJECTIVE: In clinical practice, spirometry is a extremely useful test that requires strict quality control, an appropriate strategy for interpretation, and reliable reference values. The aim of this study was to report spirometric reference values for 5 cities in Latin America.
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    Trajectories of Spirometric Patterns, Obstructive and PRISm, in a Population-Based Cohort in Latin America
    (2023) Perez-Padilla, Rogelio; de Oca, Maria Montes; Thirion-Romero, Ireri; Wehrmeister, Fernando C.; Lopez, Maria Victorina; Valdivia, Gonzalo; Jardim, Jose R.; Muino, Adriana; Menezes, Ana Maria B.; Perez-Padilla, Rogelio
    Background: Preserved ratio impaired spirometry (PRISm) has been associated with adverse outcomes and increased transition to other spirometric categories over time. We aimed to examine its prevalence, trajectories over time, and outcomes in a population-basedMethods: Data were obtained from two population-based surveys of adults from three cities in Latin America (PLATINO study), conducted on the same individuals 5-9 years after their baseline examination. We estimated the frequency of PRISm defined by FEV1 /FVC & GE;0.70 with FEV1 <80%, describing their clinical characteristics, longitudinal transition trajectories over time, factors associated with the transition.Results: At baseline, 2942 participants completed post-bronchodilator spirometry, and 2026 at both evaluations. The prevalence of normal spirometry was 78%, GOLD-stage 1 10.6%, GOLD 2-4 6.5%, and PRISm was: 5.0% (95% CI 4.2-5.8). PRISm was associated with less schooling, more reports of physician-diagnosis of COPD, wheezing, dyspnea, missing days at work, having & GE;2 exacerbations in the previous year but without accelerated lung function decline. Mortality risk was significantly higher in PRISm (HR 1.97, 95% CI 1.2-3.3) and COPD GOLD 1-4 categories (HR 1.79, 95% CI 1.3-2.4) compared with normal spirometry. PRISm at baseline most frequently transitioned to another category at follow-up (46.5%); 26.7% to normal spirometry and 19.8% to COPD. The best predictors of transition to COPD were closeness of FEV1/FVC to 0.70, older age, current smoking, and a longer FET in the second assessment.Conclusion: PRISm, is a heterogeneous and unstable condition prone to adverse outcomes that require adequate follow-up.
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    Use of respiratory medication in five Latin American cities: The PLATINO study
    (ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, 2008) de Oca, Maria Montes; Talamo, Carlos; Perez Padilla, Rogelio; Lopez, Maria Victorina; Muino, Adriana; Jardim, Jose Roberto B.; Valdivia, Gonzalo; Pertuze, Julio; Moreno, Dolores; Halbert, Ronald J.; Menezes, Ana Maria B.; PLATINO Team
    Background: There is scanty information regarding respiratory medication prescription pattern in Latin America. We examined the use of bronchodilators and corticosteroids in a population-based study conducted in five Latin American cities.