Browsing by Author "Lopez, M."
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- ItemAcute Cerebrovascular events associated to hemolytic uremic syndrome: Description of two pediatric cases(2017) Lopez, M.; Huete, Isidro; Hernández Chávez, Marta IsabelIntroduction: Diarrhea-associated Hemolytic Uremic Syndrome (D+HUS) is a multisystem disorder in which neurological involvement (35 to 50%) is associated to adverse outcome. An important cause of a permanent neurological impairment is the cerebrovascular pathology. Objective: To report two pediatric cases of D+HUS with severe neurological involvement due to cerebrovascular disease, and review available literature. Clinical cases: Two previously healthy 15- and 21-month-old children debuted with seizures and impairment of consciousness within the first week of a D+HUS. Both presented hypertension, severe acute renal failure, and focal motor deficit. One child showed significant improvement in neurologic status after five sessions of plasmapheresis. Brain magnetic resonance showed in the first child multiple bilateral infarcts of small vessels and lesions of white matter. In the second patient, large bilateral infarcts on both middle cerebral arteries territories were identified. One year after the acute event, both children showed functional impairment; The first patient evolved with language delay and spastic hemiparesis; the second patient with spastic quadriparesis, epilepsy with poor seizure control and marked functional impairment. Conclusion: Although most of the children with D+HUS and brain involvement do not have long-term sequelae, cerebrovascular disease in the acute period causes permanent damage, and in addition to the management of electrolyte disturbances, hypertension, and renal failure, therapies directed at specific pathophysiological mechanisms that trigger vascular compromise may improve prognosis.
- ItemAir Bubbles as an Admixture for Printable Concrete: A Review of the Rheological Effect of Entrained Air(2022) Eugenin, C.; Navarrete, I.; Brevis Vergara, Wernher Ariel; Lopez, M.; CEDEUS (Chile)
- ItemEffect of supplementary cementitious materials on viscosity of cement-based pastes(2022) Navarrete, I.; Kurama, Y.; Escalona, N.; Brevis Vergara, Wernher Ariel; Lopez, M.; CEDEUS (Chile)
- ItemHigh-strength self-curing low-shrinkage concrete for pavement applications(TAYLOR & FRANCIS LTD, 2010) Lopez, M.; Kahn, L. F.; Kurtis, K. E.High-performance concretes (HPC) that are designed to possess high early strength, self-curing capabilities and low shrinkage may potentially improve rigid pavement performance. A multi-scale experimental programme examined mechanical properties and shrinkage behaviour of a low water-to-cementitious materials ratio concrete containing pre-wetted lightweight aggregate for self-curing; results were compared with companion HPC prepared with air-dry lightweight aggregate and with normal weight, normal strength concrete. The use of pre-wetted lightweight aggregate enhanced hydration and strength development during the first year, and limited autogenous shrinkage and substantially reduced drying shrinkage. Digital image analysis revealed that shrinkage was concentrated in the paste rather than in the aggregate in both the normal strength concrete and HPC. The image analysis also showed that strain concentrations at the aggregate/paste interface were less apparent in the HPC, presumably due to the reduced strain mismatch with the use of the lower modulus lightweight aggregate. These observations suggest that the use of HPC containing pre-wetted lightweight aggregate can potentially reduce microcracking and enhance overall pavement performance.