Browsing by Author "Leon R., Augusto"

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    Hallazgos anatomopatológicos definitivos en pacientes tiroidectomizados con diagnóstico preoperatorio de neoplasia folicular
    (SOC CIRUJANOS CHILE, 2012) Goni E., Ignacio; Krstulovic R., Claudio; Leon R., Augusto; Gonzalez D., Hernan; Solar, Antonieta; Campusano M, Claudia; Ruiz A., Catalina
    Background: The finding of follicular neoplasm, using a FNAP, is an indication for partial or total thyroidectomy, to obtain the definitive malignant or benign histology. Frequently, it is possible to identify significant additional histological diagnosis. Aim: To obtain the definitive histological findings in patients with follicular neoplasm by FNAP. Patients and Method: Transversal analysis of 133 patients that underwent to total thyroidectomy between 2003 and 2009, that filled de requirements for adequate histological assessment. Results: In 33.1% of the treated patients the final diagnosis was indeed a follicular neoplasm (adenoma in 26.3% and cancer in 6.8%). In the 51.9% the finding was follicular colloidal hyperplasia and other thyroid cancer in 8.3%. The total malignant prevalence in the whole gland was 29.3%. Conclusions: The thyroidectomy is the treatment of choice and the final diagnostic procedure for these patients. The histological findings of cancer different from follicular not only in the punctioned nodule are a secondary and an additional argument for reinforcing the surgical indication.
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    Tiroglobulina y sus limitaciones en el seguimiento del carcinoma diferenciado del tiroides
    (2007) Velasco L., Soledad; Solar G., Antonieta; Cruz O., Francisco; Quintana F., Juan Carlos; Leon R., Augusto; Mosso G., Lorena; Fardella B., Carlos; NCD Risk Factor Collaboration (NCD-RisC)
    Thyroid carcinoma is the most prevalent endocrine tumor. and the papillary carcinoma (PC) is the most common histological type. In the follow-up, after tbyroidectomy serum thyroglobulin (s-Tg) is used as a marker to evaluate recurrence of thyroid carcinoma. In most cases, this parameter allows an adequate diagnosis,. but occasionally s-Tg may miss the detection of a recurrence. We report a 57 year old female and a 36,year old male sujected to a total thyroidectomy for a papillary thyroid carcinoma with intermediate and high-risk of recurrence. Both bad a cervical recurrence without a concomitant increase in s-Tg levels. In both, Tg staining was positive in the tumor cells. These cases confirm that in these patients, the follow-up must be done with measurement of s-Tg and complementary diagnostic tests.