Browsing by Author "Khamashta, Munther A."
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- ItemMaternal Use of Hydroxychloroquine Is Associated With a Reduced Risk of Recurrent Anti-SSA/Ro-Antibody-Associated Cardiac Manifestations of Neonatal Lupus(LIPPINCOTT WILLIAMS & WILKINS, 2012) Izmirly, Peter M.; Costedoat Chalumeau, Nathalie; Pisoni, Cecilia N.; Khamashta, Munther A.; Kim, Mimi Y.; Saxena, Amit; Friedman, Deborah; Llanos, Carolina; Piette, Jean Charles; Buyon, Jill P.Background-A recent case-control study suggested a benefit of hydroxychloroquine (HCQ) in lowering the risk of cardiac manifestations of neonatal lupus (cardiac-NL) in pregnancies of anti-SSA/Ro-positive patients with systemic lupus erythematosus. A historical cohort assembled from 3 international databases was used to evaluate whether HCQ reduces the nearly 10-fold increase in risk of recurrence of cardiac-NL independently of maternal health status.