Browsing by Author "Iturriaga, C."
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- ItemAgreement between dermatologic and pediatric researchers in scoring of atopic dermatitis in children(2014) Borzutzky Schachter, Arturo; Hoyos Bachiloglu, Rodrigo Andrés; Navarrete Dechent, Cristián Patricio; Vera Kellet, Cristián Andrés; Silva Valenzuela, Sergio; Cifuentes, Lorena; Iturriaga, C.; Cristi, F.
- ItemDeaf and hard of Hearing Students' Opportunities for Learning in a Regular Secondary School in Chile : Teacher Practices and Beliefs(2017) Lissi, María Rosa; Iturriaga, C.; Sebastián B., Christian; Vergara, M.; Henríquez, C.; Hofmann, S.
- ItemHumoral and cellular response induced by a second booster of an inactivated SARS-CoV-2 vaccine in adults(2022) Melo González, Felipe; Méndez, Constanza; Peñaloza, H.F.; Schultz, B.M.; Piña Iturbe, A.; Ríos, M.; Moreno Tapia, D.; Pereira Sánchez, P.; Leighton, D.; Orellana, C.; Covarrubias, C.; Gálvez, N.M.S.; Soto, J.A.; Duarte, L.F.; Rivera Pérez, D.; Vázquez, Y.; Cabrera, A.; Bustos, S.; Iturriaga, C.; Urzua, M.; Navarrete, M.S.; Rojas, Á.; Fasce, R.; Fernández, J.; Mora, J.; Ramírez, E.; Gaete Argel, A.; Acevedo, M.; Valiente Echeverría, F.; Soto Rifo, R.; Weiskopf, D.; Grifoni, A.; Sette, A.; Zeng, G.; Meng, W.; González Aramundiz, J.V.; González, P.A.; Abarca, K.; Bueno, S.M.; Kalergis, A.M.The SARS-CoV-2 Omicron variant has challenged the control of the COVID-19 pandemic even in highly vaccinated countries. While a second booster of mRNA vaccines improved the immunity against SARS-CoV-2, the humoral and cellular responses induced by a second booster of an inactivated SARS-CoV-2 vaccine have not been studied. In the context of a phase 3 clinical study, we report that a second booster of CoronaVac® increased the neutralizing response against the ancestral virus yet showed poor neutralization against the Omicron variant. Additionally, isolated PBMCs displayed equivalent activation of specific CD4+ T cells and IFN-γ production when stimulated with a mega-pool of peptides derived from the spike protein of the ancestral virus or the Omicron variant. In conclusion, a second booster dose of CoronaVac® does not improve the neutralizing response against the Omicron variant compared with the first booster dose, yet it helps maintaining a robust spike-specific CD4+ T cell response.
- ItemIs there an association between indoor allergens and the severity of atopic dermatitis?(2019) Cid, B.J.; Perez-Mateluna, G.; Iturriaga, C.; Zambrano, M.J.; Vives, M.I.; Valenzuela, P.M.; Borzutzky Schachter, Arturo
- ItemSafety and immunogenicity evaluation of recombinant BCG vaccine against respiratory syncytial virus in a randomized, double-blind, placebo-controlled phase I clinical trial(2020) Abarca Villaseca, Katia; Rey Jurado, Emma; Muñoz Durango, Natalia; Soto Ramírez, Jorge Andrés; Gálvez Arriagada, Nicolás Marcelo Salvador; Borzutzky Schachter, Arturo; Cerda, Jaime; Villarroel del Pino, Luis A.; González Muñoz, Pablo Alberto; González Aramundiz, José Vicente; Bueno Ramírez, Susan; Kalergis Parra, Alexis Mikes; Valdés-Ferrada, J.; Iturriaga, C.; Urzúa, M.; Madrid, V.; Bueno Ramírez, Susan; Vázquez, Y.
- ItemSevere respiratory disease caused by human respiratory syncytial virus impairs language learning during early infancy(2020) Peña, Marcela; Jara González, María Cristina; Flores, Juan Carlos; Hoyos Bachiloglu, Rodrigo Andrés; Medina Lainez, Mariana Andrea; Carcey Rivera, Javier Ignacio; Espinoza Véliz, Janyra Alejandra; Bohmwald Prieto, Karen; Kalergis Parra, Alexis Mikes; Borzutzky Schachter, Arturo; Iturriaga, C.
- ItemSleep quality in children with atopic dermatitis during flares and after treatment(2020) Kahn, D.; Iturriaga, C.; Bertran, K.; Fernandez, I.; Pérez Mateluna, G.; Borzutzky Schachter, Arturo; Brockmann Veloso, Pablo Edmundo
- ItemVitamin D modulates the allergic phenotype of dendritic cells in children with atopic dermatitis(2019) Cristi, F.; Pérez Mateluna, G.; Vera Kellet, Cristián Andrés; Silva Valenzuela, Sergio; Iturriaga, C.; Hoyos Bachiloglu, Rodrigo Andrés; Navarrete Dechent, Cristián Patricio; Cifuentes, Lorena; Camargo, C. A.; Kalergis Parra, Alexis Mikes; Borzutzky Schachter, Arturo