Browsing by Author "Hodgson, Maria I."

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    Near-optimal glycemic control in Chilean women with pregestational type-2 diabetes: Persistent macrosomia relates to maternal pre-pregnancy overweight
    (ELSEVIER IRELAND LTD, 2009) Olmos, Pablo R.; Araya Del Pino, Andrea P.; Gonzalez Carvello, Cristian A.; Laso Ulloa, Pablo; Hodgson, Maria I.; Irribarra, Veronica; Borzone, Gisella R.; Belmar, Cristian; Poblete, Andres; Berrios, Cecilia; Becker, Jorge; Zajer Amar, Claudia M.; Manzur, Alejandro; Bozinovic, Milan; Miranda, Ramon J.; Diez, Alberto; Vidal, Hernan; Ramirez Armijo, Renato; Olmos, Roberto I.; Tabilo, Cristian; Ahuad, Jessica
    After a 10-year program intending to improve glycemic control in diabetic pregnancies, we evaluated whether factors underlying macrosomia are similar for type-1 and -2 pregestational diabetic women.
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    Permanent Neonatal Diabetes and Enteric Anendocrinosis Associated With Biallelic Mutations in NEUROG3
    (AMER DIABETES ASSOC, 2011) Rubio Cabezas, Oscar; Jensen, Jan N.; Hodgson, Maria I.; Codner, Ethel; Ellard, Sian; Serup, Palle; Hattersley, Andrew T.
    OBJECTIVE-NEUROG3 plays a central role in the development of both pancreatic islets and enteroendocrine cells. Homozygous hypomorphic missense mutations in NEUROG3 have been recently associated with a rare form of congenital malabsolptive diarrhea secondary to enteroendocrine cell dysgenesis. Interestingly, the patients did not develop neonatal diabetes but childhood-onset diabetes. We hypothesized that null mutations in NEUROG3 might be responsible for the disease in a patient with permanent neonatal diabetes and severe congenital malabsorptive diarrhea.