Browsing by Author "Herrero, Rolando"
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- Item14-day triple, 5-day concomitant, and 10-day sequential therapies for Helicobacter pylori infection in seven Latin American sites: a randomised trial(ELSEVIER SCIENCE INC, 2011) Greenberg, E. Robert; Anderson, Garnet L.; Morgan, Douglas R.; Torres, Javier; Chey, William D.; Eduardo Bravo, Luis; Dominguez, Ricardo L.; Ferreccio, Catterina; Herrero, Rolando; Lazcano Ponce, Eduardo C.; Mercedes Meza Montenegro, Maria; Pena, Rodolfo; Pena, Edgar M.; Salazar Martinez, Eduardo; Correa, Pelayo; Elena Martinez, Maria; Valdivieso, Manuel; Goodman, Gary E.; Crowley, John J.; Baker, Laurence H.Background Evidence from Europe, Asia, and North America suggests that standard three-drug regimens of a proton-pump inhibitor plus amoxicillin and clarithromycin are significantly less effective for eradication of Helicobacter pylori infection than are 5-day concomitant and 10-day sequential four-drug regimens that include a nitroimidazole. These four-drug regimens also entail fewer antibiotic doses than do three-drug regimens and thus could be suitable for eradication programmes in low-resource settings. Few studies in Latin America have been done, where the burden of H pylori-associated diseases is high. We therefore did a randomised trial in Latin America comparing the effectiveness of four-drug regimens given concomitantly or sequentially with that of a standard 14-day regimen of triple therapy.
- ItemA comparison of single and combined visual, cytologic, and virologic tests as screening strategies in a region at high risk of cervical cancer(AMER ASSOC CANCER RESEARCH, 2003) Ferreccio Readi, Catterina; Bratti, María C.; Sherman, Mark E.; Herrero, Rolando; Marshall Rivera, Guillermo; Wacholder, Sholom; Hildesheim, Allan; Burk, Robert D.; Hutchinson, Martha; Alfaro, Mario; Greenberg, Mitchell D.; Morales, Jorge; Rodríguez, Ana C.; Schussler, John; Eklund, Claire; Schiffman, Mark
- ItemEpidemiology and Molecular Pathology of Gallbladder Cancer(2001) Lazcano-Ponce, Eduardo; Miquel Poblete, Juan Francisco; Muñoz, Nubia; Herrero, Rolando; Ferrecio, Catterina; Wistuba Oyarzún, Ignacio; Alonso de Ruiz, Patricia; Aristi Urista, Gerardo; Nervi Oddone, FlavioGallbladder cancer is usually associated with gallstone disease, late diagnosis, unsatisfactory treatment, and poor prognosis, We report here the worldwide geographical distribution of gallbladder cancer, review the main etiologic hypotheses, and provide some comments on perspectives for prevention. The highest incidence rate of gallbladder cancer is found among populations of the Andean area, North American Indians, and Mexican Americans. Gallbladder cancer is up to three times higher among women than men in all populations. The highest incidence rates in Europe are found in Poland, the Czech Republic, and Slovakia. Incidence rates in other regions of the world are relatively low. The highest mortality rates are also reported from South America, 3.5-15.5 per 100,000 among Chilean Mapuche Indians, Bolivians, and Chilean Hispanics. Intermediate rates, 3.7 to 9.1 per 100,000, are reported from Peru, Ecuador, Colombia, and Brazil. Mortality rates are low in North America, with the exception of high rates among American Indians in New Mexico (11.3 per 100,000) and among Mexican Americans.", "The main associated risk factors identified so far include cholelithiasis (especially untreated chronic symptomatic gallstones), obesity, reproductive factors, chronic infections of the gallbladder, and environmental exposure to specific chemicals. These suspected factors likely represent promoters of carcinogenesis. The main limitations of epidemiologic studies on gallbladder cancer are the small sample sizes and specific problems in quantifying exposure to putative risk factors. The natural history of gallbladder disease should be characterized to support the allocation of more resources for early treatment of symptomatic gallbladder disease in high-risk populations. Secondary prevention of, gallbladder cancer could be effective if supported by cost-effective studies of prophylactic cholecystectomy among asymptomatic gallstone patients in high-risk areas."]
- ItemEpidemiology of Helicobacter pylori infection in six Latin American countries (SWOG Trial S0701)(2013) Porras, Carolina; Nodora, Jesse; Sexton, Rachael; Ferreccio Readi, Catterina; Jiménez, Silvia; Domínguez, Ricardo L.; Cook Herrera, María Paz; Anderson, Garnet; Morgan, Douglas R.; Baker, Laurence H.; Greenberg, E. Robert; Herrero, Rolando
- ItemManagement of Helicobacter pylori infection in Latin America : A Delphi technique-based consensus(2014) Rollan, Antonio; Arab Verdugo, Juan Pablo; Camargo, M. Constanza; Candia Balboa, Roberto; Harris D., Paul R.; Ferreccio Readi, Catterina; Rabkin, Charles S.; Gana Ansaldo, Juan Cristóbal; Cortés, Pablo; Herrero, Rolando; Durán, Luisa; García, Apolinaria; Toledo, Claudio; Espino Espino, Alberto Antonio; Lustig, Nicole; Sarfatis Feige, Alberto; Figueroa, Catalina; Torres, Javier; Riquelme Pérez, Arnoldo
- ItemNew Approaches to Cervical Cancer Screening in Latin America and the Caribbean(ELSEVIER SCI LTD, 2008) Herrero, Rolando; Ferreccio, Catterina; Salmeron, Jorge; Almonte, Maribel; Ines Sanchez, Gloria; Lazcano Ponce, Eduardo; Jeronimo, JoseCervical cancer remains an important public health problem in the Latin America and Caribbean region (LAC), with an expected significant increase in disease burden in the next decades as a result of population ageing. Prophylactic human papillomavirus (HPV) vaccine is currently unaffordable in LAC countries, However, even if vaccination was implemented, an additional two decades will be required to observe its impact on HPV related disease and cancer. With some exceptions, cytology-based screening programs have been largely ineffective to control the problem in the region, and there is a need for new approaches to the organization of screening and for use of newly developed techniques. Several research groups in LAC have conducted research on new screening methods, some of which are summarized in this paper. A recommendation to reorganize screening programs is presented considering visual inspection for very low resource areas, improvement of cytology where it is operating successfully and HPV DNA testing followed by visual inspection with acetic acid (VIA) or cytology as soon as this method becomes technically and economically sustainable. This could be facilitated by the incorporation of new, low-cost HPV DNA testing methods and the use of self-collected vaginal specimens for selected groups of the population. An important requisite for screening based on HPV testing will be the quality assurance of the laboratory and the technique by validation and certification measures. (C) 2008 Elsevier Ltd. All rights reserved.
- ItemReproductive factors, oral contraceptive use, and human papillomavirus infection: Pooled analysis of the IARC HPV prevalence surveys(AMER ASSOC CANCER RESEARCH, 2006) Vaccarella, Salvatore; Herrero, Rolando; Dai, Min; Snijders, Peter J. F.; Meijer, Chris J. L. M.; Thomas, Jaiye O.; Hoang Anh, Pham Thi; Ferreccio, Catterina; Matos, Elena; Posso, Hector; de Sanjose, Silvia; Shin, Hai Rim; Sukvirach, Sukhon; Lazcano Ponce, Eduardo; Ronco, Guglielmo; Rajkumar, Raj; Qiao, You Lin; Munoz, Nubia; Franceschi, Silvia; IARC HPV Prevalence SurveystHigh parity, early age at first full-term pregnancy (FTP), and long-term oral contraceptive (OC) use increase cervical cancer risk, but it is unclear whether these variables are also associated with increased risk of acquisition and persistence of human papillomavirus (HPV) infection, the main cause of cervical cancer. Information on reproductive and menstrual characteristics and OC use were collected from 14 areas worldwide, among population-based, age-stratified random samples of women aged 15 years or older. HPV testing was done using PCR-based enzyme immunoassay. Unconditional logistic regression was used to estimate the odds ratios (OR) of being HPV-positive according to reproductive and menstrual factors and corresponding 95% confidence intervals (CI). When more than two groups were compared, floating CIs (FCI) were estimated. A total of 15,145 women (mean age, 40.9 years) were analyzed. Women with >= 5 FTPs (OR, 0.90; 95% FCI, 0.76-1.06) showed a similar risk of being HPV-positive compared with women with only one FTP (OR, 1.00; 95% FCI, 0.86-1.16). However, nulliparous women showed an OR of 1.40 (95% CI, 1.16-1.69) compared with parous women. Early age at first FTP was not significantly related to HPV positivity. HPV positivity was similar for women who reported >= 10 years of use of OCs (OR, 1.16; 95% FCI, 0.85-1.58) and never users of OCs (OR, 1.00; 95% FCI, 0.90-1.12). Our study suggests, therefore, that high parity, early age at first FTP, and long-term OC use are not associated with HPV prevalence, but rather these factors might be involved in the transition from HPV infection to neoplastic cervical lesions.
- ItemSmoking and human papillomavirus infection: pooled analysis of the International Agency for Research on Cancer HPV Prevalence Surveys(OXFORD UNIV PRESS, 2008) Vaccarella, Salvatore; Herrero, Rolando; Snijders, Peter J. F.; Dai, Min; Thomas, Jaiye O.; Hieu, Nguyen Trong; Ferreccio, Catterina; Matos, Elena; Posso, Hector; de Sanjose, Silvia; Shin, Hai Rim; Sukvirach, Sukhon; Lazcano Ponce, Eduardo; Munoz, Nubia; Meijer, Chris J. L. M.; Franceschi, Silvia; IHPS Study GrpBackground Smoking increases the risk of squamous-cell carcinoma of the cervix, but it is not clear whether smoking increases the risk of acquisition or persistence of human papillomavirus (HPV) infection.
- ItemVariations in the age-specific curves of human papillomavirus prevalence in women worldwide(WILEY-BLACKWELL, 2006) Franceschi, Silvia; Herrero, Rolando; Clifford, Gary M.; Snijders, Peter J. F.; Arslan, Annie; Anh, Pham Thi Hoang; Bosch, F. Xavier; Ferreccio, Catterina; Hieu, Nguyen Trong; Lazcano Ponce, Eduardo; Matos, Elena; Molano, Monica; Qiao, You Lin; Rajkumar, Raj; Ronco, Guglielmo; de Sanjose, Silvia; Shin, Hai Rim; Sukvirach, Sukhon; Thomas, Jaiye O.; Meijer, Chris J. L. M.; Munoz, Nubia; ISRC Prevalence Surveys Study GrpAn inverse relationship between age and human papillomavirus (HPV) prevalence has been reported in many developed countries, but information on this relationship is scarce in many other parts of the world. We carried out a cross-sectional study of sexually active women from the general population of 15 areas in 4 continents. Similar standardised protocols for women's enrolment, cervical specimen collection and PCR-based assays for HPV testing were used. HPV prevalence in different age groups was compared by study area. 18,498 women aged 15-74 years were included. Age-standardised HPV prevalence varied more than 10-fold between populations, as did the shape of age-specific curves. HPV prevalence peaked below age 25 or 35, and declined with age in Italy, the Netherlands, Spain, Argentina, Korea and in Lampang, Thailand and Ho Chi Minh, Vietnam. This was not the case in Songkla, Thailand nor Hanoi, Vietnam, where HPV prevalence was low in all age groups. In Chile, Colombia and Mexico, a second peak of HPV prevalence was detected among older women. In the poorest study areas in Asia (Shanxi, China and Dindigul, India), and in Nigeria, HPV prevalence was high across all age groups. The substantial differences observed in age-specific curves of HPV prevalence between populations may have a variety of explanations. These differences, however, underline that great caution should be used in inferring the natural history of HPV from age-specific prevalences. (c) 2006 Wiley-Liss, Inc.