Browsing by Author "Guzmán, Pablo"

Now showing 1 - 4 of 4
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    Comentarios y observaciones. Indicaciones a proyecto de Ley de Integración Social y Urbana en segundo trámite parlamentario
    (2020) Fuentes, Luis; Guzmán, Pablo; Méndez, María; Moris, Roberto; Orellana, Arturo; Ruiz-Tagle, Javier; Vicuña, Magdalena
    El presente documento de trabajo corresponde a un esfuerzo colectivo de análisis de parte de los académicos del Instituto de Estudios Urbanos y Territoriales de la Pontificia Universidad Católica de Chile, con observaciones y propuestas al Proyecto de Ley sobre Integración Social y Urbana, con el objetivo de contribuir a mejorar dicha iniciativa presentada por el gobierno y aportar elementos de juicio para la discusión parlamentaria.
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    Early gallbladder carcinoma has a favorable outcome but Rokitansky-Aschoff sinus involvement is an adverse prognostic factor
    (2013) Roa Strauch, Juan Carlos Enrique; Tapia,Oscar; Manterola, Carlos; Villaseca, Miguel; Guzmán, Pablo; Araya, Juan Carlos; Bagci, Pelin; Saka, Burcu; Adsay, Volkan
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    Exploring the Genetic Diversity of Epstein–Barr Virus among Patients with Gastric Cancer in Southern Chile
    (2023) Reyes, María Elena; Zanella, Louise; Riquelme, Ismael; Buchegger, Kurt; Mora-Lagos, Bárbara; Guzmán, Pablo; García Cañete, Patricia; Roa Strauch, Juan Carlos Enrique; Gloria Ili, Carmen; Brebi, Priscilla
    The Epstein–Barr virus (EBV) has been associated with gastric cancer (GC), one of the deadliest malignancies in Chile and the world. Little is known about Chilean EBV strains. This study aims to investigate the frequency and genetic diversity of EBV in GC in patients in southern Chile. To evaluate the prevalence of EBV in GC patients from the Chilean population, we studied 54 GC samples using the gold standard detection method of EBV-encoded small RNA (EBER). The EBV-positive samples were subjected to amplification and sequencing of the Epstein–Barr virus nuclear protein 3A (EBNA3A) gene to evaluate the genetic diversity of EBV strains circulating in southern Chile. In total, 22.2% of the GC samples were EBV-positive and significantly associated with diffuse-type histology (p = 0.003). Phylogenetic analyses identified EBV-1 and EBV-2 in the GC samples, showing genetic diversity among Chilean isolates. This work provides important information for an epidemiological follow-up of the different EBV subtypes that may cause GC in southern Chile.
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    Frecuencia de la infección por Chlamydia trachomatis en un grupo de mujeres de la Región de la Araucanía, Chile
    (2013) Silva, Ramón; León, Daniela; Viscarra, Támara; Ili, Carmen; Roa Strauch, Juan Carlos Enrique; Sánchez, Raúl; Guzmán, Pablo; Brebi, Priscilla