Browsing by Author "Ferrer Márquez, Fernando Andrés"
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- ItemCirugía bariátrica previo a embarazo y su impacto en el resultado perinatal; revision de la literatura(2016) Ferrer Márquez, Fernando Andrés; Mundaca, Manuel; Ledezma Ledezma, Alejandra; Carvajal C., Jorge A.
- ItemClinical application of amino-terminal pro-brain natriuretic peptide concentration in amniotic fluid for the prediction of preterm birth in symptomatic women(2024) Ferrer Márquez, Fernando Andrés; Astudillo Goic, Rocío Pilar; Carvajal C., Jorge A.BACKGROUND: Preterm birth accounts for 60% to 80% of neonatal mortality. Approximately one-third of preterm births are caused by the spontaneous onset of preterm labor. Nevertheless, 70% to 90% of women diagnosed with preterm labor will not deliver within 7 days. Thus, many women will be unnecessarily treated by preterm labor with risk medications. Better tools are needed to categorize women in preterm labor into high or low risk of preterm delivery.OBJECTIVE: This study aimed to evaluate the amino-terminal pro-brain natriuretic peptide concentration in the amniotic fluid as a prognostic test to predict the risk of delivery within 48 hours or 7 days and before 34 0/7 or 37 0/7 weeks of gestation in women in preterm labor.STUDY DESIGN: A total of 102 pregnant women presenting signs and symptoms of spontaneous preterm birth (22 0/7 to 34 0/7 weeks of gestation) were included. Amniotic fluid was obtained by amniocentesis, and amino-terminal pro-brain natriuretic peptide concentration was measured. Below normal concentration was defined as <0.5 multiples of the median of the standard curve according to gestational age. The risk of preterm delivery was estimated according to normal or lower-than-normal amino-terminal pro-brain natriuretic peptide concentrations. The predictive capacity of the test (below normal amino-terminal pro-brain natriuretic peptide concentration) was evaluated to identify spontaneous preterm birth at 48 hours or 7 days from amniocentesis and less than 34 0/7 or 37 0/7 weeks at delivery.RESULTS: For the outcome delivery within 48 hours, lower-than-normal amino-terminal pro-brain natriuretic peptide concentration had 94.6% sensitivity, 73.8% specificity, 96.0% negative predictive value, 3.61 positive likelihood ratio, and 0.07 negative likelihood ratio. For the outcome delivery within 7 days, the test had 93.9% sensitivity, 88.7% specificity, 94.0% negative predictive value, 8.31 positive likelihood ratio, and 0.07 negative likelihood ratio. For the outcomes of spontaneous preterm birth before 34 0/7 and 37 0/7 weeks of gestation, below normal amino-terminal pro-brain natriuretic peptide concentrations had 80.0% sensitivity, 83.0% specificity, 78.0% negative predictive value, 4.70 positive likelihood ratio, and 0.24 negative likelihood ratio and 64.1% sensitivity, 91.7% specificity, 44.0% negative predictive value, 7.70 positive likelihood ratio, and 0.39 negative likelihood ratio, respectively.CONCLUSION: Among patients in spontaneous preterm labor, the detection of lower-than-normal amino-terminal pro-brain natriuretic peptide concentrations (<0.5 multiples of the median) in amniotic fluid has an excellent predictive capacity to identify those patients at low risk of preterm delivery within 48 hours or 7 days.
- ItemComparación entre Ondansetrón y Doxilamina más Piridoxina para el tratamiento de las náuseas en el embarazo(2015) Ferrer Márquez, Fernando Andrés; Carvajal C., Jorge A.
- ItemComparison of two identification and susceptibility test kits forUreaplasmaspp andMycoplasma hominisin amniotic fluid of patients at high risk for intra-amniotic infection(2020) Kusanovic, Juan Pedro; Vargas Innocenti, Paula Andrea; Ferrer Márquez, Fernando Andrés; Díaz, F.; Córdova, V.; Martinovic, C.; Valdés, R.; Rosas, A.; Luna Fernández, Daniela Fanny; Silva, P.; Silva, K.; Nilo, M. E.; Silva, M. J.; Espejo, E.; Zambrano, M. A.; García, J.; Parra Lara, L. G.; Escobar, M. F.
- ItemNormal amino-terminal pro-brain natriuretic peptide (NT-proBNP) values in amniotic fluid(2017) Carvajal C., Jorge A.; Ferrer Márquez, Fernando Andrés; Araya, F.; Delpiano, A.
- ItemResultado de estudio prenatal invasivo para el diagnóstico de aneuploidía en el Hospital Sótero del Río(2016) Vargas Innocenti, Paula Andrea; Sepúlveda M., Sebastián; Kusanovic, Juan Pedro; Parra, Zasha; Mellado Sagredo, Cecilia; Pardo, Rosa; Silva, Karla; Díaz, Francisco; Ferrer Márquez, Fernando Andrés; Córdova, Víctor; Valdés, Rafael; Martinovic, Carolina; Salas, Carolina; Cortés, Patricio
- ItemRevista de Revistas. Uso de corticoides antenatales en fetos de término o cercanos al término : revisión sistemática y meta-análisis de estudios aleatorizados controlados(2016) Ferrer Márquez, Fernando Andrés; Solari, Caterina; Carvajal C., Jorge A.
- ItemTransabdominal collection of amniotic fluid "sludge" and identification of Candida albicans intra-amniotic infection(2018) Kusanovic, Juan Pedro; Romero, Roberto; Martinovic, Carolina; Silva, Karla; Erez, Offer; Maymon, Eli; Diaz, Francisco; Ferrer Márquez, Fernando Andrés; Valdes, Rafael; Cordova, Victor; Vargas Innocenti, Paula Andrea; Elena Nilo, Maria; Le Cerf, Patricio