Browsing by Author "Espinoza, J."
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- ItemA New Hybrid Filter Topology for Sub and Inter-Harmonic Attenuation in Cycloconverter-Fed Drives Applications(IEEE, 2009) Aravena, P.; Moran, L.; Dixon Rojas, Juan; Espinoza, J.; Godoy, O.This paper presents a filter scheme composed by passive and series active power filters specially designed to compensate fundamental reactive power (with passive filters) and current harmonics (combination of passive and active). Low frequency current sub and inter-harmonics generated by cycloconverters are eliminated with an active power filter connected in series to a C type passive filter. Current frequency harmonics associated with cycloconverter topology are eliminated with passive filter units. With the proposed filter topology compensation effectiveness is significantly improved and allows the elimination of passive filter units, reducing cost and space required as compared with traditional passive schemes. This paper presents the principles of operation and design requirements of the proposed hybrid filter scheme. Simulated results based in the compensation of a real grinding mill plant prove the effectiveness and advantages of the proposed scheme.
- ItemA rapid MMP-8 bedside test for the detection of intra-amniotic inflammation identifies patients at risk for imminent preterm delivery(2006) Nien, J. K.; Yoon, B. H.; Espinoza, J.; Kusanovic, Juan Pedro; Erez, O.; Soto, E.; Richani, K.; Gómez Mora, Ricardo Alberto; Hassan, S.; Mazor, M.; Edwin, S.; Bahado-Singh, R.; Romero, R.Objective: Matrix metalloproteinase-8 (MMP-8) is an enzyme that is released during neutrophil activation. MMP-8 amniotic fluid concentrations are elevated not only in patients with intra-amniotic infection, but also in patients with negative amniotic fluid cultures who deliver preterm neonates. The objective of this study was to determine whether the results of a rapid MMP-8 bedside test predict imminent preterm delivery. This test can be performed in 15 minutes and without laboratory equipment. Study design: Amniotic fluid was retrieved from 331 patients admitted with increased preterm uterine contractions and intact membranes who met the inclusion criteria. Amniotic fluid was processed for microbial cultures, Gram stain, glucose concentration, and white blood cell count. Amniotic fluid samples were stored, and the MMP-8 rapid test was performed after delivery. End points included spontaneous preterm delivery within 48 hours, 7 days, and 14 days. Diagnostic indices, predictive values, and likelihood ratios were calculated. Results: The prevalence of spontaneous preterm delivery within 48 hours, 7 days, and 14 days was 11.6% (38/327), 20.2% (66/327), and 24.5% (80/327), respectively (4 patients with augmentation of labor were excluded). A positive MMP-8 rapid test had a positive predictive value of 70% (23/33) for the identification of patients who delivered spontaneously within 48 hours, and 94% (31/33) for patients who were delivered within 7 days and 14 days (likelihood ratios: 17.5 [95% CI, 9-33.9], 61.3 [95% CI, 15.1-250], and 50 [95% CI, 12-196], respectively). Conclusion: The MMP-8 rapid test can identify patients at risk for preterm delivery within 7 days and 14 days. Moreover, a positive MMP-8 rapid test result can identify patients with intraamniotic infection/inflammation with a high sensitivity and specificity. This rapid test will give clinicians a fast and accurate assessment of the inflammatory status of the amniotic cavity and allow for better identification of patients at risk for impending preterm delivery.
- ItemAdiponectin in severe preeclampsia(2007) Nien, J. K.; Mazaki-Tovi, S.; Romero, R.; Erez, O.; Kusanovic, Juan Pedro; Gotsch, F.; Pineles, B. L.; Gómez Mora, Ricardo Alberto; Edwin, S.; Mazor, M.; Espinoza, J.; Yoon, B. H.; Hassan, S. S.Aims: Adiponectin is an adipokine with insulin-sensitizing, anti-atherogenic, anti-inflammatory and angiogenic properties. The aims of this study were to determine whether maternal plasma adiponectin concentrations differ between patients with severe preeclampsia and those with normal pregnancies, and to explore the relationship between plasma adiponectin and the results of Doppler velocimetry of the uterine arteries. Methods: This case-control study included two groups: (1) patients with severe preeclampsia (ns50) and (2) patients with normal pregnancies (ns150). Pulsedwave and color Doppler ultrasound examination of the uterine arteries were performed. Plasma adiponectin concentrations were determined by ELISA. Non-parametric statistics were used for analysis. Results: (1) Patients with severe preeclampsia had a higher median plasma concentration of adiponectin than that of normal pregnant women. (2) The median plasma adiponectin concentration did not differ between women with severe preeclampsia who had a high impedance to blood flow in the uterine arteries and those with normal impedance to blood flow. (3) Among patients with normal pregnancies, plasma adiponectin concentrations were negatively correlated with BMI in the first trimester and at sampling. Conclusions: Women with severe preeclampsia have a higher median plasma concentration of adiponectin than that of normal pregnant women. This may reflect a compensatory feedback mechanism to the metabolicallyaltered, anti-angiogenic and pro-atherogenic state of severe preeclampsia.
- ItemFirst-trimester maternal serum PP13 in the risk assessment for preeclampsia(2008) Romero, R.; Kusanovic, J.P.; Than, N.G.; Erez, O.; Gotsch, F.; Espinoza, J.; Edwin, S.; Chefetz, I.; Gomez, R.; Nien, J.K.; Sammar, M.; Pineles, B.; Hassan, S.S.; Meiri, H.; Tal, Y.; Kuhnreich, I.; Papp, Z.; Cuckle, H.S.
- ItemFunctional Impairment of Mononuclear Phagocyte System by the Human Respiratory Syncytial Virus(2017) Bohmwald Prieto, Karen; Espinoza, J.; Pulgar, R.; Jara, E.; Kalergis Parra, Alexis Mikes
- ItemmiR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway(2016) Riquelme, I.; Tapia, O.; Leal, P.; Sandoval, A.; Varga, M.; Letelier, P.; Buchegger, K.; Bizama, Carolina; Espinoza, J.; Peek, R.; Araya, J.; Roa Strauch, Juan Carlos Enrique
- ItemPreeclampsia is associated with low concentrations of protein Z(2007) Erez, O.; Hoppensteadt, D.; Romero, R.; Espinoza, J.; Goncalves, L.; Nien, J.K.; Kusanovic, J.P.; Fareed, J.; Gotsch, F.; Pineles, B.; Chaiworapongsa, T.
- ItemPrelabor Rupture of the Membranes(2008) Santolaya-Forgas, J.; Romero, R.; Espinoza, J.; Erez, O.; Friel, L.A.; Kusanovic, J.P.; Bahado-Singh, R.; Nien, J.K.
- ItemPrenatal diagnosis of coarctation of the aorta with the multiplanar display and B-flow imaging using 4-dimensional sonography(2009) Espinoza, J.; Romero, R.; Kusanovic, J.P.; Gotsch, F.; Erez, O.; Hassan, S.; Yeo, L.
- ItemPrenatal diagnosis of truncus arteriosus using multiplanar display in 4D ultrasonography(2010) Gotsch, F.; Romero, R.; Espinoza, J.; Kusanovic, J.P.; Erez, O.; Hassan, S.; Yeo, L.
- ItemProteomic analysis of amniotic fluid to identify women with preterm labor and intra-amniotic inflammation/infection: The use of a novel computational method to analyze mass spectrometric profiling(2008) Romero, R.; Espinoza, J.; Rogers, W.T.; Moser, A.; Kae Nien, J.; Pedro Kusanovic, J.; Gotsch, F.; Erez, O.; Gomez, R.; Edwin, S.; Hassan, S.S.
- ItemResistin: A hormone which induces insulin resistance is increased in normal pregnancy(2007) Nien, J.K.; Mazaki-Tovi, S.; Romero, R.; Kusanovic, J.P.; Erez, O.; Gotsch, F.; Pineles, B.L.; Friel, L.A.; Espinoza, J.; Goncalves, L.; Santolaya, J.; Gomez, R.; Hong, J.-S.; Edwin, S.; Soto, E.; Richani, K.; Mazor, M.; Hassan, S.S.
- ItemSoluble receptor for advanced glycation end products (sRAGE) and endogenous secretory RAGE (esRAGE) in amniotic fluid: Modulation by infection and inflammation(2008) Romero, R.; Espinoza, J.; Hassan, S.; Gotsch, F.; Kusanovic, J.P.; Avila, C.; Erez, O.; Edwin, S.; Schmidt, A.M.
- ItemThe fetal inflammatory response syndrome(2007) Gotsch, F.; Romero, R.; Kusanovic, J.P.; Mazaki-Tovi, S.; Pineles, B.L.; Erez, O.; Espinoza, J.; Hassan, S.S.
- ItemThe transcriptome of the fetal inflammatory response syndrome(2010) Madsen-Bouterse, S.A.; Romero, R.; Tarca, A.L.; Kusanovic, J.P.; Espinoza, J.; Kim, C.J.; Kim, J.-S.; Edwin, S.S.; Gomez, R.; Draghici, S.
- ItemTwin-to-twin transfusion syndrome: an antiangiogenic state?(2008) Kusanovic, J.P.; Romero, R.; Espinoza, J.; Nien, J.K.; Kim, C.J.; Mittal, P.; Edwin, S.; Erez, O.; Gotsch, F.; Mazaki-Tovi, S.; Than, N.G.; Soto, E.; Camacho, N.; Gomez, R.; Quintero, R.; Hassan, S.S.
- ItemUncoupled inflammatory, proliferative, and cytoskeletal responses in senescent human gingival fibroblasts(2020) Páez, J.; Hernández Salinas, Romina; Rojas Cortéz, Leticia Andrea; Espinoza, J.; Martínez, Constanza; Tobar, N.; Martínez, J.; Smith, P. C.