Browsing by Author "Escobar, Juan J."

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    ICD-10 coded hospitalizations due to drug hypersensitivity: A nationwide study from Chile
    (ELSEVIER, 2020) Escobar, Juan J.; Aguilera Insunza, Raquel; Borzutzky Schachter, Arturo; Hoyos Bachiloglu, Rodrigo
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    Increasing food allergies in Chile, a developing country post-epidemiological transition
    (WILEY, 2020) Hoyos Bachiloglu, Rodrigo; Escobar, Juan J.; Cifuentes, Camila; Aguilera Insunza, Raquel; Morales, Pamela S.; Borzutzky, Arturo
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    Universal Access to On-Demand Treatment of Patients with Hereditary Angioedema, the Chilean Experience
    (2023) Escobar, Juan J.; Aguirre, Joaquin; Ibanez, Samuel; Cid, Barbara J.; Campillay, Rolando; Gallardo, Ana Maria; Grau, Masumi; Hoyos-Bachiloglu, Rodrigo
    Background: In Chile, patients with hereditary angioedema (HAE) type I and type II are protected under Ley Ricarte Soto (LRS), which guarantees access to on demand plasma-derived C1-INH (pdC1-INH) since 2018. We aimed to analyze the first 3 years of LRS.Methods: Review of the LRS database between 2018 and 2021.Results: During the study period, 154 patients were covered by LRS, with an estimated prevalence of HAE in Chile at 0.8:100,000 inhabitants. A delay in diagnosis of 22 years was noted, 50 patients received epinephrine during an attack before the diagnosis of HAE. Mean number of attacks per year was 8, with 50% of adults and 42% of children experiencing more than 1 attack per month.Conclusion: Disease awareness must improve to reduce the diagnostic delay of HAE. Long-term prophylactic medications should be included in LRS to treat patients with high attack rates and control the costs of frequent on-demand treatment with pdC1-INH.