Browsing by Author "Echeverría González, Francisca Cecilia"

Now showing 1 - 9 of 9
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    A Feasible Approach to Developing Fiber-Enriched Bread Using Pomegranate Peel Powder: Assessing Its Nutritional Composition and Glycemic Index
    (2023) García, Paula; Bustamante, Andrés; Echeverría González, Francisca Cecilia; Encina, Cristian; Palma, Manuel; Sanhueza, Leyla; Sambra, Verónica; Pando, Maria Elsa; Jiménez, Paula
    The consumption of dietary fiber (DF) has been associated with a reduced incidence of non-communicable diseases. Despite various strategies implemented worldwide to increase DF intake, it remains low. Therefore, the development of new fiber-rich food products that are widely consumed could be a strategy to improve DF intake. In this study, an agro-industrial by-product, pomegranate peel powder (PPP), was used as an innovative source of DF and antioxidant. The objective was to develop a bread enriched with DF, antioxidants, and sensory characteristics by partially replacing wheat flour (WF) with PPP at levels of 0%, 2.5%, 5%, 7.5%, and 10%. Bread with 2.5% and 5% PPP was chosen for a clinical trial to evaluate glycemic response (GR) in healthy subjects and determine the bread’s glycemic index (GI). As the percentage of PPP increased, both the DF and total polyphenol content increased significantly. The highest overall acceptability was achieved with bread containing up to 5% PPP. Consumption of bread with 2.5% and 5.0% PPP significantly reduced the GI compared to the control bread, while the decrease in GR was not significant. PPP could be a potential food and low-cost ingredient to improve the bread’s nutritional quality through its contribution to DF and antioxidants.
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    Beneficial Effects of Bioactive Compounds Obtained from Agro-Industrial By-Products on Obesity and Metabolic Syndrome Components
    (2022) Jeria, Nicolas; Cornejo, Sebastian; Prado, Gabriel; Bustamante, Andres; Garcia-Diaz, Diego F.; Jimenez, Paula; Valenzuela, Rodrigo; Poblete-Aro, Carlos; Echeverría González, Francisca Cecilia
    The generation of agro-industrial by-products is an economic and environmental problem. However, these raw materials could be a suitable source for obtaining bioactive compounds for technological or nutritional purposes. On the other hand, obesity and metabolic syndrome prevalence are in continuous growth. The classical approach of hypocaloric diet and exercise has shown little long-term adherence. Thus, there is an unending search for new strategies to prevent and treat obesity and related metabolic alterations. In that sense, the revalorization of agro-industrial by-products for functional foods and nutraceutical development has gained relevance. Pomegranate, onion, and grape by-products, among others, have been described as promising raw materials for bioactive compounds obtention. Nevertheless, scientific evidence on the effects of specific sources and bioactive compounds on obesity models and clinical trials is needed. This article aims to show available data from studies on the effect of bioactive compounds obtained from agro-industrial by-products on obesity and metabolic syndrome components.
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    Deep-frying impact on food and oil chemical composition: Strategies to reduce oil absorption in the final product
    (John Wiley and Sons Inc, 2024) Valle, Consuelo; Echeverría González, Francisca Cecilia; Chávez, Vilma; Valenzuela, Rodrigo; Bustamante, Andrés
    During frying, oils can deteriorate due to autoxidation and hydrolytic alterations, processes influenced by the oil's fatty acid composition (FAC) and antioxidant content. However, there are different techniques to improve fried food quality and reduce oil absorption. This review aims to assess existing literature on the interactions between frying methods, oil selection, and the chemical composition of foods. To achieve this goal, the article examines the impact of oil FAC, antioxidants, pretreatments, and alternative frying technologies. A literature search was conducted from 2016 to 2023. The keywords used were (AND/OR) frying, fried foods, oil, oil absorption, and fatty acids. Oils rich in monounsaturated fatty acids and antioxidants, such as olive oil, are recommended for their nutritional benefits and improved oil stability. The water content and structure of the food also play a significant role in oil absorption. Pretreatments to diminish food moisture content contribute to a lower oil absorption in the fried food while mitigating excessive accumulation of lipid oxidation products. Proper selection of frying oils, incorporation of antioxidants, and the use of pretreatments could help prevent chemical changes and minimize oil absorption during frying. These measures contribute to maintaining the nutritional quality and safety of fried foods while also enhancing their overall sensory appeal.
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    Dietary and Nutritional Interventions in Nonalcoholic Fatty Liver Disease in Pediatrics
    (2023) Farías, Camila; Cisternas, Camila; Gana Ansaldo, Juan Cristóbal; Alberti, Gigliola; Echeverría González, Francisca Cecilia; Videla, Luis A.; Mercado, Lorena; Muñoz, Yasna; Valenzuela, Rodrigo
    Nonalcoholic fatty liver disease (NAFLD) is pediatrics’ most common chronic liver disease. The incidence is high in children and adolescents with obesity, which is associated with an increased risk of disease progression. Currently, there is no effective drug therapy in pediatrics; therefore, lifestyle interventions remain the first line of treatment. This review aims to present an updated compilation of the scientific evidence for treating this pathology, including lifestyle modifications, such as exercise and dietary changes, highlighting specific nutritional strategies. The bibliographic review was carried out in different databases, including studies within the pediatric population where dietary and/or nutritional interventions were used to treat NAFLD. Main interventions include diets low in carbohydrates, free sugars, fructose, and lipids, in addition to healthy eating patterns and possible nutritional interventions with n-3 polyunsaturated fatty acids (EPA and DHA), amino acids (cysteine, L-carnitine), cysteamine, vitamins, and probiotics (one strain or multi-strain). Lifestyle changes remain the main recommendation for children with NAFLD. Nevertheless, more studies are required to elucidate the effectiveness of specific nutrients and bioactive compounds in this population.
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    n-3 polyunsaturated fatty acids in the regulation of adipose tissue browning and thermogenesis in obesity: Potential relationship with gut microbiota
    (2021) Zapata, J.; Gallardo, A.; Romero, C.; Valenzuela, R.; Garcia-Diaz, D. F.; Duarte, L.; Bustamante, A.; Gasaly, N.; Gotteland, M.; Echeverría González, Francisca Cecilia
    Background: Obesity is a worldwide public health problem characterized by fat tissue accumulation, favouring adipose tissue and metabolic alterations. Increasing energy expenditure (EE) through brown adipose tissue activation and white adipose tissue (WAT) browning has gained relevance as a therapeutic approach. Different bioactive compounds, such as n-3 polyunsaturated fatty acids (PUFA), have been shown to induce those thermogenic effects. This process is regulated by the gut microbiota as well. Nevertheless, obesity is characterized by gut microbiota dysbiosis, which can be restored by weight loss and n-3 PUFA intake, among other factors. Knowledge gap: However, the role of the gut microbiota on the n-3 PUFA effect in inducing thermogenesis in obesity has not been fully elucidated. Objective: This review aims to elucidate the potential implications of this interrelation on WAT browning adiposw sittue (BAT), BAT activity, and EE regulation in obesity models.
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    N-3 PUFAs and their specialized pro-resolving lipid mediators on airway inflammatory response: beneficial effects in the prevention and treatment of respiratory diseases
    (2022) Zúñiga-Hernández, Jessica; Sambra, Verónica; Echeverría González, Francisca Cecilia; Videla, Luis A.; Valenzuela, Rodrigo
    Respiratory diseases include a wide range of pathologies with different clinical manifestations, affecting the normal airways and lung function. An increase in the inflammatory response is considered a characteristic hallmark of these diseases, being also a critical factor for their progression. The n-3 polyunsaturated fatty acids (n-3 PUFAs) eicosapentaenoic acid (C20:4n-3, EPA), docosahexaenoic acid (C22:6n-3, DHA) and their lipid mediators are known to have an inflammation pro-resolution effect. The effects of these n-3 PUFAs in the prevention and treatment of respiratory diseases are beginning to be understood. Consequently, this article aims to analyze the influence of n-3 PUFAs and their lipid mediators on the inflammatory response in respiratory health, emphasizing recent data concerning their beneficial effects in the prevention and possible treatment of different respiratory diseases, particularly asthma, airway allergic syndromes and chronic obstructive pulmonary disease. The review includes studies regarding the effects of EPA, DHA, and their specialized pro-resolving lipid mediators (SPMs) on in vivo and in vitro models of respiratory disease, concluding that EPA and DHA have a positive impact in attenuating the pro-inflammatory response in respiratory diseases, reducing symptoms like nasal congestion, fever and difficulty in breathing. Controversial data reported are probably due to differences in several factors, including the dosages, administration vehicles, and the supplementation times employed, which are aspects that remain to be addressed in future studies.
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    Polyphenols in the Prevention and Treatment of Non-communicable Diseases
    (2022) Echeverría González, Francisca Cecilia; Valenzuela, Rodrigo
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    Potencial efecto terapéutico de los polifenoles obtenidos de la cáscara de granada en la esteatosis hepática
    (2022) Bustamante, Andres; Garcia-Diaz, Diego; Jimenez, Paula; Valenzuela, Rodrigo; Pando, Maria Elsa; Echeverría González, Francisca Cecilia
    Antecedentes: La enfermedad por hígado graso no alcohólico (EHGNA) tiene una elevada prevalencia a nivel mundial, y puede ir desde la esteatosis simple hasta hepatocarcinoma. Su origen es multifactorial, siendo la dieta poco saludable un factor clave en su patogenia y progresión. Los polifenoles son antioxidantes que han mostrado beneficios en el tratamiento de la EHGNA. Una fuente emergente de estos compuestos son los residuos agroindustriales, entre ellos, la cáscara de granada. La cáscara de granada tiene un alto contenido de polifenoles, específicamente de elagitaninos. Su extracto fenólico (extracto de cáscara de granada; ECG) ha mostrado efectos promisorios a nivel metabólico. Sin embargo, su uso presenta algunas limitantes que deben ser consideradas antes de recomendar su ingesta mediante alimentos funcionales o nutracéuticos para prevención o tratamiento de EHGNA. Objetivo: Discutir a partir de datos obtenidos en estudios in vitro y modelos animales, el potencial terapéutico de los polifenoles obtenidos de la cáscara de granada para prevención y tratamiento de la EHGNA. Metodología: Se realizó una búsqueda bibliográfica en bases de datos PubMed y Web of Science (2015 a la fecha) de estudios en modelos de esteatosis hepática in vitro y en animales, además de ensayos clínicos relacionados. Conclusión: Existen datos promisorios sobre el uso del ECG en alteraciones metabólicas propias de la EHGNA y esteatosis hepática, principalmente a nivel de perfil lipídico. Se deben discutir las dosis y formas de administración, con el fin de mejorar su estabilidad y biodisponibilidad. Se requieren ensayos clínicos controlados que confirmen los efectos en humanos.
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    Revalorización de residuos de arándano: Extracción polifenólica con tecnologías emergentes y convencionales
    (2024) Reinoso, Yessenia; Herrera, Edgar; Ortiz, Jaime; Echeverría González, Francisca Cecilia; Bustamante, Andrés
    The blueberry juice industry generates residues after processing the fruit that could negatively impact the environment. However, blueberry by-products are rich in phenolic compounds, especially anthocyanins, which have shown positive health effects. Therefore, its revalorization for the formulation of functional ingredients becomes interesting. However, obtaining bioactive compounds from blueberry waste depends mainly on technology. Our objective is to discuss the effect of different conventional and emerging extraction technologies, such as ultrasound-assisted extraction, accelerated solvent extraction, and supercritical-CO2 extraction, in obtaining polyphenolic compounds from blueberry residues. As result, both conventional and emerging methods effectively recover polyphenolic compounds from the blueberry residue (Vaccinium spp.). However, extraction with emerging methods has other advantages since they are considered friendly to the environment by consuming less energy and using suitable solvents for the food industry.