Browsing by Author "Dreyse, Jorge"
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- ItemBehavior of Quality of Life (SGRQ) in COPD Patients According to BODE Scores. Comportamiento de la calidad de vida (SGRQ) en pacientes con EPOC según las puntuaciones BODE(2015) Nonato, Nívia L.; Díaz Patiño, Orlando; Nascimento, Oliver A.; Dreyse, Jorge; Jardim, José R.; Lisboa Basualto, Carmen
- ItemCPAP in patients with obstructive sleep apnea and type 2 diabetes mellitus: Systematic review and meta-analysis(2018) Labarca, Gonzalo; Reyes, Tomas; Jorquera, Jorge; Dreyse, Jorge; Drake, Lauren
- ItemDificultades en la elección de una ecuación de referencia para la interpretación de los resultados de capacidad de difusión de monóxido de carbono(2013) Briceño Villafane, Catalina Paz; Dreyse, Jorge; Mendoza L., Laura; Díaz Patiño, Orlando; Mercado M., Gesma; Borzone, Gisella
- ItemEffects of changes in trunk inclination on ventilatory efficiency in ARDS patients: quasi-experimental study(2023) Benites, Martín H.; Torres, David; Poblete, Fabián; Labbé, Francisco; Bachmann, María C.; Regueira, Tomas E.; Soto, Leonardo; Ferre, Andrés; Dreyse, Jorge; Retamal Montes, JaimeTrunk inclination from semirecumbent head-upright to supine-flat positioning reduces driving pressure and increases respiratory system compliance in patients with acute respiratory distress syndrome (ARDS). These effects are associated with an improved ventilatory ratio and reduction in the partial pressure of carbon dioxide (PaCO2). However, these physiological effects have not been completely studied, and their mechanisms have not yet been elucidated. Therefore, this study aimed to evaluate the effects of a change in trunk inclination from semirecumbent (45°) to supine-flat (10°) on physiological dead space and ventilation distribution in different lung regions. Results: twenty-two ARDS patients on pressure-controlled ventilation underwent three 60-min steps in which trunk inclination was changed from 45° (baseline) to 10° (intervention) and back to 45° (control) in the last step. Tunk inclination from a semirecumbent (45°) to a supine-flat (10°) position resulted in a higher tidal volume [371 (± 76) vs. 433 (± 84) mL (P < 0.001)] and respiratory system compliance [34 (± 10) to 41 (± 12) mL/cmH2O (P < 0.001)]. The CO2 exhaled per minute improved from 191 mL/min (± 34) to 227 mL/min (± 38) (P < 0.001). Accordingly, Bohr’s dead space ratio decreased from 0.49 (± 0.07) to 0.41 (± 0.06) (p < 0.001), and PaCO2 decreased from 43 (± 5) to 36 (± 4) mmHg (p < 0.001). In addition, the impedance ratio, which divides the ventilation activity of the ventral region by the dorsal region ventilation activity in tidal images, dropped from 1.27 (0.83–1.78) to 0.86 (0.51–1.33) (p < 0.001). These results, calculated from functional EIT images, indicated further ventilation activity in the dorsal lung regions. These effects rapidly reversed once the patient was repositioned at 45°. Conclusions: a change in trunk inclination from a semirecumbent (45 degrees) to a supine-flat position (10 degrees) improved Bohr’s dead space ratio and reduced PaCO2 in patients with ARDS. This effect is associated with an increase in tidal volume and respiratory system compliance, along with further favourable impedance ventilation distribution toward the dorsal lung regions. This study highlights the importance of considering trunk inclination as a modifiable determinant of physiological parameters. The angle of trunk inclination is essential information that must be reported in ARDS patients.
- ItemEtiology of community-acquired pneumonia in hospitalized patients in Chile - The increasing prevalence of respiratory viruses among classic pathogens(ELSEVIER SCIENCE BV, 2007) Diaz, Alejandro; Barria, Paulina; Niederman, Michael; Restrepo, Marcos I.; Dreyse, Jorge; Fuentes, Gino; Couble, Bernardita; Saldias, FernandoBackground and study objectives: The range and relative impact of microbial pathogens, particularly viral pathogens, as a cause of community-acquired pneumonia (CAP) in hospitalized adults has not received much attention. The aim of this study was to determine the microbial etiology of CAP in adults and to identify the risk factors for various specific pathogens.
- ItemHipertensión pulmonar en pacientes con fibrosis pulmonar y sobrevida post-trasplante pulmonar(2016) Briceño Villafane, Catalina Paz; Sepúlveda, Claudia; Melo T., Joel; Linacre S., Virginia; Dreyse, Jorge