Browsing by Author "Del Rio, R."

Now showing 1 - 4 of 4
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    A potentiostatic and atomic force Microscopy study of the nucleation and growth mechanisms of certain metallic cyanometalates
    (AMER CHEMICAL SOC, 2007) Orellana, M.; Del Rio, R.; Schrebler, R.; Cordova, R.
    Nucleation and growth mechanisms (NGMs) of nickel(II) hexacyanoferrate, nickel(II) octacyanomolibdate, and copper(II) octacyanomolibdate were performed by means of the potential step technique by oxidizing the respective metal electrode in 0.02 M sulfuric acid containing the potassium salt of either hexacyanoferrate or octacyanomolibdate compounds. The obtained current-time transients (I/t) were analyzed using the theory of electrocrystallization of the metallic phase. As evidenced through these experiments, we can state that for the nickel cyanometalate compounds, electroformation takes place through a three-dimensional progressive NGM, and for the copper(II) octacyanomolibdate compound, electroformation occurs by means of a three-dimensional instantaneous NGM. The electrochemical results were verified through the use of atomic force microscopy (AFM). From these results, we can conclude that AFM is a good complementary technique to determine the nature of the NGMs through which electroformation of a solid phase occurs on an electrode surface.
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    Heart rate variability alterations in infants with spontaneous hypertonia
    (2019) Arce-Alvarez, A.; Melipillan, C.; Andrade Andrade, David Cristóbal; Toledo, C.; Marcus, N.J.; Del Rio, R.
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    Kinematic and Neuromuscular Measures of Intensity During Plyometric Jumps
    (2017) Andrade Andrade, David Cristóbal; Manzo, O.; Beltran, A.; Álvarez, C.; Del Rio, R.; Toledo, C.; Moran, J.; Ramirez Campillo, R.
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    Neurocognitive Disorders in Heart Failure: Novel Pathophysiological Mechanisms Underpinning Memory Loss and Learning Impairment
    (SPRINGER, 2019) Toledo, C.; Andrade, D. C.; Diaz, H. S.; Inestrosa, N. C.; Del Rio, R.
    Heart failure (HF) is a major public health issue affecting more than 26 million people worldwide. HF is the most common cardiovascular disease in elder population; and it is associated with neurocognitive function decline, which represent underlying brain pathology diminishing learning and memory faculties. Both HF and neurocognitive impairment are associated with recurrent hospitalization episodes and increased mortality rate in older people, but particularly when they occur simultaneously. Overall, the published studies seem to confirm that HF patients display functional impairments relating to attention, memory, concentration, learning, and executive functioning compared with age-matched controls. However, little is known about the molecular mechanisms underpinning neurocognitive decline in HF. The present review round step recent evidence related to the possible molecular mechanism involved in the establishment of neurocognitive disorders during HF. We will make a special focus on cerebral ischemia, neuroinflammation and oxidative stress, Wnt signaling, and mitochondrial DNA alterations as possible mechanisms associated with cognitive decline in HF. Also, we provide an integrative mechanism linking pathophysiological hallmarks of altered cardiorespiratory control and the development of cognitive dysfunction in HF patients.