Browsing by Author "Copaja, M."
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- ItemEarly expression of monocyte chemoattractant protein-1 correlates with the onset of isoproterenol-induced cardiac fibrosis in rats with distinct angiotensin-converting enzyme polymorphism(2008) Copaja, M.; Ocaranza, María Paz; Jalil Milad, Jorge; Vio Lagos, Carlos P.
- ItemSimvastatin alters fibroblastic cell responses involved in tissue repair(WILEY-BLACKWELL, 2011) Caceres, M.; Romero, A.; Copaja, M.; Diaz Araya, G.; Martinez, J.; Smith, P. C.Background and Objective: Statins have been used to control hypercholesterolemia. However, these drugs also exert pleiotropic effects that include the modulation of inflammation and cell signaling. The present study has analyzed the effects of simvastatin on several cell responses involved in tissue repair, including cell adhesion, cell migration and invasion, actin cytoskeleton remodeling and cell viability.