Browsing by Author "Catalán, P."
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- ItemAnalysis of voriconazole serum concentrations and safety profile in pediatric oncology patients,Análisis de concentraciones plasmáticas de voriconazol y su perfil de seguridad en pacientes oncológicos pediátricos(2016) Silva Marambio, F.; Navea, D.; Salas, C.; Torres, J.P.; Catalán, P.; Morales, J.
- ItemBarred-beach morphological control on infragravity motion(2012) Almar, R.; Cienfuegos Carrasco, Rodrigo Alberto; Gonzalez, Eduardo; Catalán, P.; Michallet, H.; Bonneton, P.; Castelle, B.; Suarez, L.A conceptual analysis of the coupling between bars and infragravity waves is performed combining laboratory experiments and numerical modeling. Experiments are carried out in a wave flume with a barred profile. The Boussinesq fully-nonlinear model SERR1D is validated with the laboratory data and a sensitivity analysis is performed next to study the influence on the infragravity wave dynamics of bar amplitude and location, and swash zone slope. A novel technique of incident and reflected motions separation that conserves temporal characteristics is applied. We observe that changing bar characteristics induces substantial variations in trapped energy. Interestingly, a modification of swash zone slope has a large influence on the reflected component, controlling amplitude and phase time-lag, and consequently on the resonant pattern. Variations of trapped infragravity energy induced by changes of swash zone slope reach 25 %. These changes in infragravity pattern consequently affect short-wave dynamics by modifying the breakpoint location and the breaking intensity. Our conceptual investigation suggests the existence of a morphological feedback through the action of evolving morphology on infragravity structures which modulates the action of short-waves on the morphology itself.
- ItemNearshore bathymetric inversion from video using a fully non-linear Boussinesq wave model(2011) Cienfuegos Carrasco, Rodrigo Alberto; Almar, R.; Birrien, F.; Castelle, B.; Catalán, P.; Michallet, H.This paper presents a new depth inversion methodology from video imagery. The strength of the method is the use of a fully non-linear Boussinesq wave model in combination with a very complete video-derived laboratory wave observation that includes period, celerity and wave height. Compared to the previous use of wave dispersion formulas, here the better description of wave dynamics substantially improves bathymetry estimation. For the considered laboratory case, error on bathymetry is as small as 8 % whereas other formulations, shallow water or non-linear derived solution can only attain 24 % and 14 %, respectively. More in-depth analysis on the error shows a fair sensitivity on video-derived breaker height and describes the large contribution of non-linearities. The recent possibility of using Serre's dispersion relation in combination with video-derived wave height provides a reasonable performance and should be further envisaged for one-dimensional depth inversion. Future extensions of this work involve the use of a two-dimensional Boussinesq model to include more hydrodynamics processes such as wave-driven circulation over three-dimensional surfzone sandbars.
- ItemPharmacokinetics of posaconazol in the prophylaxis and treatment of invasive fungal infection in immunocompromised children in a pediatric hospital,Farmacocinética de posaconazol en la profilaxis y tratamiento de la infección fúngica invasora en niños inmunocomprometidos en un hospital pediátrico(2018) Valenzuela, R.; García, P.; Barraza, M.; Palma, J.; Catalán, P.; Santolaya, M.E.; Torres, J.P.; Morales Vallespín, J.
- ItemProfilaxis de infección por virus respiratorios en niños y adultos sometidos a trasplante de órganos sólidos y precursores hematopoyéticos(2012) Álvarez, A.M.; Catalán, P.; Alba, A.; Zubieta, M.
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- ItemProphylaxis against Toxoplasma gondii disease in pediatric and adult patients undergoing solid organ and hematopoietic stem cells transplantation,Profilaxis de toxoplasmosis en niños y adultos sometidos a trasplante de órganos sólidos y precursores hematopoyéticos(2012) Payá, E.; Noemí, I.; Tassara, R.; Catalán, P.; Avilés, C.L.
- ItemVideo monitoring and field measurements of a rapidly evolving coastal system: the river mouth and sand spit of the Mataquito River in Chile(2014) Cienfuegos Carrasco, Rodrigo Alberto; Villagrán, M.; Aguilera, José Miguel; Catalán, P.; Castelle, B.; Almar, R.