Browsing by Author "Castillo, Oscar"
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- ItemAssociation of carotid intima media thickness with blood pressure and HDL cholesterol in children(SOC MEDICA SANTIAGO, 2012) Arnaiz, Pilar; Villarroel, Luis; Barja, Salesa; Godoy, Ivan; Cassis, Berta; Dominguez, Angelica; Castillo, Oscar; Farias, Marcelo; Carvajal, Jacqueline; Cristina Tinoco, Ana; Mardones, FranciscoBackground: Cardiovascular risk factors must be controlled since childhood. Aim: To assess the association of carotid intima media thickness (CIMT) with the components of the metabolic syndrome in Children. Material and Methods: Cross sectional assessment of 299 children aged 11.5 +/- 0.9 years (58% women) with and without metabolic syndrome components. Anthropometric parameters and blood pressure were measured and a blood sample was obtained to measure blood glucose and lipids. CIMT was measured using high resolution ultrasound. Results: Ninety three percent of children were post puberal, 64% were overweight and 25% had metabolic syndrome. Mean and maximum CIMT correlated with systolic blood pressure (r = 0.21 and 0.21 respectively p < 0.01). Children with a CIMT over the 75th percentile had higher blood pressure and lower HDL cholesterol. A stepwise logistic regression accepted both variables as predictors of CIMT with odds ratios for mean CIMT of 1.46 (1.19-1-79) and 0.81 (0.7-0.94) per five units of change, respectively. Conclusions: In this group of children systolic blood pressure and HDL cholesterol are associated to CIMT. (Rev Med Chile 2012; 140: 1268-1275).
- ItemAteroesclerosis subclinica y sindrome metabolic en ninos(AULA MEDICA EDICIONES, 2013) Arnaiz, Pilar; Barjal, Salesa; Villarroel, Luis; Dominguez, Angelica; Godoy, Ivan; Castillo, Oscar; Farias, Marcelo; Mardones, FranciscoIntroduction: Metabolic syndrome (MS) in children has been associated to subclinical atherosclerosis as estimated by carotid intima-media thickness (CIMT).
- ItemEffects of a dairy product fortified with multiple micronutrients and omega-3 fatty acids on birth weight and gestation duration in pregnant Chilean women(CAMBRIDGE UNIV PRESS, 2008) Mardones, Francisco; Urrutia, Maria Teresa; Villarroel, Luis; Rioseco, Alonso; Castillo, Oscar; Rozowski, Jaime; Tapia, Jose Luis; Bastias, Gabriel; Bacallao, Jorge; Rojas, Ivanobjective: To test the hypothesis that maternal food fortification with omega-3 fatty acids and multiple micronutrients increases birth weight and gestation duration, as primary outcomes.
- ItemHealth impact of Mediterranean diets in food at work(CAMBRIDGE UNIV PRESS, 2009) Leighton, Federico; Polic, Gianna; Strobel, Pablo; Perez, Druso; Martinez, Carlos; Vasquez, Luis; Castillo, Oscar; Villarroel, Luis; Echeverria, Guadalupe; Urquiaga, Ines; Mezzano, Diego; Rozowski, JaimeObjective: To evaluate the feasibility of diet mediterranisation, in a food-at-work context, and its consequence on metabolic syndrome in a mid-age unselected healthy male Population group.
- ItemNormal plasma insulin and HOMA values among chilean children and adolescents(SOC MEDICA SANTIAGO, 2011) Barja, Salesa; Arnaiz, Pilar; Dominguez, Angelica; Villarroel, Luis; Cassis, Berta; Castillo, Oscar; Salomo, Gianina; Farias, Marcelo; Goycoolea, Manuela; Quiroga, Teresa; Mardones, FranciscoBackground: Plasma insulin and HOMA (homeostasis model assessment) index, used to determine insulin resistance, do not have local standard values for children and adolescents in Chile. Aim: To establish the normal reference intervals for insulin and HOMA in children and adolescents aged 10-15 years, according to sex and puberal maturation. Material and Methods: A cross-sectional study of 2,153 children and adolescents from Puente Alto County was performed, during 2009 and 2010. Anthropoinetry and self-report of puberal maturation were assessed. Fasting glucose (hexoquinase) and insulin blood levels (chemiluminiscence), were determined and HOMA index was calculated. Percentile distributions of these variables were calculated. Results: The reference group included only subjects with normal body mass index and fasting blood glucose (n = 1,192). Girls had higher insulin and HOMA values than boys (12.5 +/- 6.0 and 9.1 +/- 4.9 mu U/mL (p <0.01) and 2.7 +/- 1.4 and 2.1 +/- 1,1 (p <0.01), respectively). Subjects with Tanner land II puberal stages had lower insulin and HOMA mean values than subjects with Tanner III and IV (9.0 +/- 4.3 and 12.5 +/- 6.2 mu U/ml (p < 0.01) and 2.0 +/- 1 and 2.8 +/- 1.4 (p <0.01), respectively). Conclusions: The 90th percentile of insulin and HOMA distributions according to sex and maturation, was selected as the upper cut-off point to identify individuals with insulin resistance. HOMA cutoff point for Tanner I and II boys was 3.2, for Tanner land II girls was 4.1, for Tanner III and IV boys was 4.2 and for Tanner III and IV girls was 5.0. (Rev Med Chile 2011; 139: 1435-1443).
- ItemNutritional profile of schoolchildren from different socio-economic levels in Santiago, Chile(CAMBRIDGE UNIV PRESS, 2011) Liberona, Yessica; Castillo, Oscar; Engler, Valerie; Villarroel, Luis; Rozowski, JaimeObjective: To assess the nutritional status, food intake and physical activity patterns in schoolchildren attending 5th and 6th grade in basic schools from different socio-economic levels in the metropolitan region of Santiago.
- ItemNUTRITIONAL STATUS, METABOLIC SYNDROME AND INSULIN RESISTANCE IN CHILDREN FROM SANTIAGO (CHILE)(ARAN EDICIONES, S L, 2013) Mardones, Francisco; Arnaiz, Pilar; Barja, Salesa; Giadach, Carolina; Villarroel, Luis; Dominguez, Angelica; Castillo, Oscar; Farias, MarceloBackground: The origin of most non-communicable diseases (NCDs) is in early life. Consequently obtaining information on risk factors for NCDs is important for preventive purposes. However, there is no information available on the prevalence of obesity, metabolic syndrome (MS) and insulin resistance (IR) in Chilean children.
- ItemPrenatal Growth and Metabolic Syndrome Components in Children(2011) Mardones S., Francisco; Villarroel del Pino, Luis A.; Barja, Salesa; Arnaíz, Pilar; Castillo, Oscar; Farías, Marcelo; Domínguez, Angélica