Browsing by Author "Campolo González, Andrés Francisco"

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    Cleft lip and palate surgery simulator: Open source simulation model
    (Elsevier Ltd, 2024) Teuber Lobos, Cristian Andrés; Benítez, Benito K.; Lill, Yoriko; Kiser, Laura E.; Tache, Ana; Fernández Pose, María; Campolo González, Andrés Francisco; Nalabothu, Prasad; Sharma, Neha; Thieringer, Florian M.; Vargas Díaz, Alex Patricio; Mueller, Andreas A.
    Objective: Cleft lip and palate is the most common craniofacial birth anomaly and requires surgery in the first year of life. However, craniofacial surgery training opportunities are limited. The aim of this study was to present and evaluate an open-source cleft lip and palate hybrid (casting and three-dimensional (3D) printing) simulation model which can be replicated at low cost to facilitate the teaching and training of cleft surgery anatomy and techniques. Design: The soft tissue component of the cleft surgery training model was casted using a 3D printed 5-component mold and silicone. The bony structure was designed to simulate the facial anatomy and to hold the silicone soft tissue. Setting: Two groups, one group of trainees and one group of expert surgeons, at University Hospital Basel in Switzerland and Pontifical Catholic University of Chile in Santiago, Chile, tested the cleft lip and palate simulation model. Participants completed a Likert-based face and content validity questionnaire to assess the realism of the model and its usefulness in surgical training. Results: More than 70 % of the participants agreed that the model accurately simulated human tissues found in patients with unilateral cleft lip and palate. Over 60 % of the participants also agreed that the model realistically replicated surgical procedures. In addition, 80–90 % of the participants found the model to be a useful and appropriate tool for teaching the anatomy and surgical techniques involved in performing unilateral cleft lip and palate repair. Conclusion: This open-source protocol provides a cost-effective solution for surgeons to introduce the cleft morphology and surgical techniques to trainees on a regular basis. It addresses the current financial barrier that limits access to commercially available models during the early stages of surgeon training prior to specialization in the field.
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    Effects of hypotensive anesthesia compared to normotensive anesthesia in orthognathic surgeryEfectos de la anestesia hipotensora comparada con la anestesia normotensora en cirugía ortognática
    (2024) Dallaserra Albertini, Matías; Vargas Buratovic Juan Pablo; Campolo González, Andrés Francisco; Ríos Espósito, Nicolás; Nazar Jara, Claudio; Valladares Pérez, Salvador Rubén; Ortuño Borroto, Duniel
    Introduction: Orthognathic surgery is widely accepted for correcting dentofacial deformities. Due to the rich blood supply in the head and neck region, considerable bleeding can occur from the incised soft tissues and bone during orthognathic surgery. Hypotensive anesthesia is a method used in surgical practice by which blood pressure is decreased predictably and deliberately to reduce blood loss and improve surgical field. However, there is still uncertainty regarding its effectiveness and safety in orthognathic surgery. Methods: We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. We extracted data from the systematic reviews, reanalyzed data of primary studies, conducted a meta-analysis, and generated a summary of findings table using the GRADE approach. Results and Conclusions: We identified three systematic reviews, including 11 studies overall, which are randomized trials. We concluded that hypotensive anesthesia may reduce intraoperative blood loss and may improve the quality of surgical field, however, the certainty of the evidence has been assessed as low. On the other hand, orthognathic surgery with HA may make little or no difference in surgical time (low certainty evidence). Finally, no studies were found that reported adverse effects or mortality.Introducción: La cirugía ortognática se encuentra ampliamente aceptada para la corrección de anomalías dentofaciales. Debido al importante suministro de sangre en la región de cabeza y cuello, puede ocurrir una considerable pérdida de sangre proveniente de los tejidos duros y blandos intervenidos durante una cirugía ortognática. La anestesia hipotensiva es un método utilizado en la práctica quirúrgica mediante el cual se disminuye de manera predecible y deliberada la presión sanguínea con el fin de reducir la pérdida hemática y mejorar el campo quirúrgico. Sin embargo, aún existe incertidumbre respecto a su efectividad y seguridad en cirugía ortognática. Métodos: Realizamos una búsqueda en Epistemonikos, la mayor base de datos de revisiones sistemáticas en salud, la cual es mantenida mediante el cribado de múltiples fuentes de información, incluyendo MEDLINE, EMBASE, Cochrane, entre otras. Extrajimos los datos desde las revisiones identificadas, analizamos los datos de los estudios primarios, realizamos un metanálisis y preparamos una tabla de resumen de los resultados utilizando el método GRADE. Resultados y Conclusiones: Identificamos tres revisiones sistemáticas, que en conjunto incluyeron 11 estudios primarios, todos ensayos aleatorizados. Concluimos que la anestesia hipotensiva podría reducir la pérdida de sangre intraoperatoria y mejorar la calidad del campo quirúrgico, pero la certeza de la evidencia es baja. Por otro lado, el uso de anestesia hipotensiva podria podría resultar en poca o nula diferencia en el tiempo quirúrgico (certeza de la evidencia baja). Finalmente, no se encontraron estudios que reportaran efectos adversos o mortalidad.
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    Use of autologous platelet derivatives for secondary alveoloplasty in patients with cleft lip and palate: a protocol for a systematic review and meta-analysis
    (2021) Campolo González, Andrés Francisco; Heider Contreras, Claudia Andrea; Cañete Campos, Ismael Ignacio; Verdugo Paiva, María Francisca; Bravo Jeria, Rocío; Morovic, Carmen Gloria; Rada Giacamán, Gabriel Alejandro
    Objective: To assess the effectiveness and safety of autologous platelet derivatives, specifically platelet-rich plasma (PRP) or platelet-rich fibrin (PRF), for secondary alveoloplasty in patients with cleft lip and palate. Eligibility criteria: We will include randomized trials evaluating the effect of autologous platelet derivatives on newly bone formed after secondary alveoloplasty in cleft lip and palate patients. Two reviewers will independently screen each study for eligibility, data extraction, and bias assessment using the Cochrane "risk of bias" tool. We will pool the results using meta-analysis and apply the GRADE system to assess the certainty of the evidence for each outcome. Data sources: A comprehensive search will include all relevant randomized controlled trials (RCTs), the ongoing investigation reported in specialty congresses and trials regardless of language or ublication status (published, unpublished, in press, and progress). We will conduct searches in the following databases: Cochrane Central Register of Controlled Trials (CENTRAL), PUBMED, Embase, and LILACS. We will screen trial registries and other sources in order to identify articles that might have been missed in the electronic searches. Ethics and dissemination: As researchers will not access information that could identify an individual participant, obtaining ethical approval was waived.
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    Use of autologous platelet derivatives for secondary alveoloplasty in patients with cleft lip and palate: a systematic review and meta-analysis
    (Churchill Livingstone, 2024) Campolo González, Andrés Francisco; Heider Contreras, Claudia Andrea; Verdugo Paiva, M. F.; Bravo Jeria, R.; Morovic, C. G.; Rada, G.
    This study aimed to evaluate the effectiveness of autologous platelet derivatives (APD), specifically platelet-rich plasma (PRP) or platelet-rich fibrin (PRF), combined with autogenous iliac crest bone grafts in secondary alveoloplasty for patients with cleft lip and palate. Electronic databases, relevant journals, and reference lists of included studies were searched until July 2022. Best-evidence synthesis was performed to draw conclusions. After the search strategies, 12 randomized controlled trials were included that provided data on six outcomes: newly formed bone, mean bone loss in height and width, bone density, functionality, and postoperative complications. Two authors independently assessed the risk of bias, and the certainty of evidence was assessed using the GRADE approach. The pooled results suggest that there is uncertainty as to whether the combination of APDs with autogenous iliac crest bone grafts improves the percentage of newly formed bone, as the certainty of the evidence was assessed as very low. It may slightly improve the functionality of patients (with low certainty of the evidence) and probably slightly reduces the incidence of postoperative complications (with moderate certainty of evidence). Further randomized clinical trials with standardized methodologies are required to validate these findings.