Browsing by Author "Bustamante, Andrea"

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    Mini bronchoalveolar lavage in patients with severe respiratory failure
    (SOC MEDICA SANTIAGO, 2011) Andresen, Max; Mercado, Marcelo; Zapata, Marcelo; Bustamante, Andrea; Regueira, Tomas
    Background: To recognize the etiological agent responsible for severe acute respiratory failure (ARF) in patients in mechanical ventilation (MV) is important to determine their treatment and prognosis, and to avoid the excessive use of antibiotics. Mini bronchoalveolar lavage (mini BAL) is a blind, non bronschoscopic procedure, used to obtain samples from the lower respiratory tract from patients on mechanical ventilation (MV). Aim: To assess the feasibility, complications and preliminary results of mini BAL among patients with severe ARF on MV Material and Methods: Prospective study in 17 patients with acute lung injury (ALI) or acute respiratory distess syndrome (ARDS) on MV and with negative conventional microbiological studies. Mini BAL was performed using standardized protocols. Hemodynamic and respiratory parameters where measured before and after the procedure. Samples obtained were sent to quantitative cultures. Results: At baseline: APACHE II score of 22 +/- 6,7, P(a)O(2)/F(i)O(2) ratio was 176.6 +/- 48.6 and the oxygenation index was 9.74 +/- 3.78. All procedures were performed by an ICU resident. Thirty five percent of the procedures had positive cultures and no complications related to the procedures were reported. The procedure lasted an average of 12 minutes and the instilled and rescued volume were 60 ml and 19.6 ml, respectively There were no significant differences between hemodynamic and respiratory variables before and after the procedure. Conclusions: Mini BAL is a safe, fast and easy technique for obtaining samples from the inferior airway in patients with ALI or ARDS on MV (Rev Med Chile 2011; 139: 1292-1297).
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    Optimal length of triple therapy for H pylori eradication in a population with high prevalence of infection in Chile
    (BAISHIDENG PUBLISHING GROUP INC, 2007) Riquelme, Arnoldo; Soza, Alejandro; Pedreros, Cesar; Bustamante, Andrea; Valenzuela, Felipe; Otarola, Francisco; Abbott, Eduardo; Arellano, Marco; Medina, Brenda; Pattillo, Alejandro; Greig, Douglas; Arrese, Marco; Rollan, Antonio
    AIM: To compare the efficacy of 7-d versus 14-d triple therapy for the treatment of H pylori infection in Chile, with a prevalence of 73% in general population. METHODS: H pylori-infected patients diagnosed by rapid urease test, with non-ulcer dyspepsia or peptic ulcer disease were randomized to receive omeprazole 20 mg bid, amoxicillin 1 g bid, and clarithromycin 500 mg bid for 7 (OAC7) or 14 (OAC14) d. Primary outcome was eradication rate 6 wk after the treatment. Subgroup analysis was carried out considering the eradication rate among patients with or without peptic ulcer disease and eradication rate among smokers or non-smokers.
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    The boundaries of mild chronic obstructive pulmonary disease (COPD): design of the searching clinical COPD onset (SOON) study
    (2017) Labarca, Gonzalo; Bustamante, Andrea; Valdivia Cabrera, Gonzalo; Díaz Montero, Rodrigo Aquiles; Huete, Isidro; Mac Nab, Paul; Mendoza, Laura; Leppe, Jaime; Lisboa Basualto, Carmen; Saldías Peñafiel, Fernando; Díaz, Orlando