Browsing by Author "Briones, Juan"

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    A systematic review and meta-analysis of artificial intelligence versus clinicians for skin cancer diagnosis
    (2024) Salinas, María Paz; Sepúlveda, Javiera; Hidalgo, Leonel; Peirano, Dominga; Morel, Macarena; Uribe, Pablo; Rotemberg, Verónica; Briones, Juan; Mery, Domingo; Navarrete-Dechent, Cristian
    Scientific research of artificial intelligence (AI) in dermatology has increased exponentially. The objective of this study was to perform a systematic review and meta-analysis to evaluate the performance of AI algorithms for skin cancer classification in comparison to clinicians with different levels of expertise. Based on PRISMA guidelines, 3 electronic databases (PubMed, Embase, and Cochrane Library) were screened for relevant articles up to August 2022. The quality of the studies was assessed using QUADAS-2. A meta-analysis of sensitivity and specificity was performed for the accuracy of AI and clinicians. Fifty-three studies were included in the systematic review, and 19 met the inclusion criteria for the meta-analysis. Considering all studies and all subgroups of clinicians, we found a sensitivity (Sn) and specificity (Sp) of 87.0% and 77.1% for AI algorithms, respectively, and a Sn of 79.78% and Sp of 73.6% for all clinicians (overall); differences were statistically significant for both Sn and Sp. The difference between AI performance (Sn 92.5%, Sp 66.5%) vs. generalists (Sn 64.6%, Sp 72.8%), was greater, when compared with expert clinicians. Performance between AI algorithms (Sn 86.3%, Sp 78.4%) vs expert dermatologists (Sn 84.2%, Sp 74.4%) was clinically comparable. Limitations of AI algorithms in clinical practice should be considered, and future studies should focus on real-world settings, and towards AI-assistance.
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    Author Correction: A systematic review and meta-analysis of artificial intelligence versus clinicians for skin cancer diagnosis
    (2024) Salinas Espinoza, María Paz; Sepúlveda, Javiera; Hidalgo, Leonel; Peirano, Dominga; Morel, Macarena; Uribe, Pablo; Rotemberg, Verónica; Briones, Juan; Mery, Domingo; Navarrete Dechent, Cristian Patricio
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    Complete response to immunotherapy plus chemotherapy after an unusual clinical response to afatinib and stereotactic radiosurgery in a patient with metastatic EGFR-mutant non–small-cell lung cancer
    (2020) Pizarro, Gonzalo; Pinto, Mauricio P.; Muñoz-Medel, Matías; Cordova-Delgado, Miguel; Bravo, M. Loreto; Nervi, Bruno; Sánchez, César; Ibañez, Carolina; Peña, José; Walbaum, Benjamín; Madrid, Jorge; Briones, Juan; Koch, Erica; Valbuena, Jose; Gonzalez, Sergio; Gejman, Roger; Acevedo, Francisco; Mondaca, Sebastian; Garrido, Marcelo; Vines, Eugenio; Galindo, Hector
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    Regorafenib adjusted dose for Chilean patients with chemoresistant metastatic colorectal cancer: a case series
    (2018) Leal, José Luis; Briones, Juan; Herrera, María Elisa; Müller, Bettina; Nervi Nattero, Bruno; Mondaca Contreras, Sebastián Patricio