Browsing by Author "Bravo, Loreto"
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- ItemPPAR alpha and PPAR gamma regulate the nucleoside transporter hENT1(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2012) Montero, Trinidad D.; Racordon, Dusan; Bravo, Loreto; Owen, Gareth I.; Bronfman, Miguel L.; Leisewitz, Andrea V.Human equilibrative nucleoside transporter 1 (hENT1) is an important determinant for nucleoside analog based chemotherapy success. Preliminary data suggest hENT1 regulation by PPARs. Using A2780 cells, we investigated the role of PPARs on hENT1 expression and activity.