Browsing by Author "Barja Y., Salesa"

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    Acute effect of ketotifen on the dose-response curve of histamine and methacholine in asthma
    (1985) Lisboa Basualto, Carmen; Moreno Bolton, Rodrigo; Cruz, E.; Barja Y., Salesa; Sánchez Díaz, Ignacio; Morán, J.; Ferretti Daneri, Ricardo
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    Anemia and iron deficiency in children with chronic respiratory diseases
    (2013) Barja Y., Salesa; Capo, Eduardo; Briceño, Lilian; Jakubson, Leticia; Méndez Raggi, Mireya; Becker Kossen, Ana
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    Aprendizaje interprofesional en los internados de las carreras de la salud del Hospital Josefina Martínez
    (2020) Barañao Garcés, Patricio; Villagrán Gutiérrez, Ignacio Andrés; Moya Osorio, José Luis; Jeldes Díaz, Paz Ximena; Calvo Sánchez, María Fernanda; Fuentes López, Eduardo; Barja Y., Salesa
    Introducción: las dinámicas de atención en salud requieren que los profesionales que componen el equipo de salud trabajen en forma colaborativa. Sin embargo, durante su formación, las oportunidades de aprendizaje con otras disciplinas son escasas. Se reportan los resultados del primer proyecto para promover el aprendizaje interprofesional en los internos que rotan por el Hospital Josefina Martínez. Método: de marzo a julio 2018, se realizó un taller constituido por dos sesiones, en cada rotación de internado. Participaron internos de cinco carreras en forma conjunta (kinesiología, odontología, nutrición, fonoaudiología y terapia ocupacional). Se adaptó la encuesta de disposición al aprendizaje interprofesional, para ser aplicada antes y después de cada taller. Se calcularon las medianas, rangos intercuartílicos (Q1; Q3 y se compararon los puntajes mediante test de Wilcoxon. Resultados: hubo una disposición positiva inicial al aprendizaje interprofesional, con mejoría significativa después de los talleres en todas las dimensiones de la encuesta: Trabajo en equipo y colaboración (<0,001), trabajo centrado en el paciente (<0,001), y sentido de identidad profesional (<0,05). La diferencia del puntaje global de la encuesta también fue significativa (<0,001). Conclusiones: se demostró un cambio favorable y significativo en las respuestas de los internos después de los talleres, en todas las dimensiones de la encuesta. En los comentarios, destacaron la relevancia de aprender con estudiantes de otras carreras, describiendo que aumentó su conocimiento sobre éstas y reforzando el impacto que dicha integración tiene en mejorar la atención y resolución de problemas en salud.
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    ASSOCIATION BETWEEN PERINATAL FACTORS AND COMPONENTS OF THE METABOLIC SYNDROME AND INSULIN RESISTANCE IN CHILDREN OF PUENTE ALTO, SANTIAGO, CHILE
    (2013) Mardones, Francisco; Pacheco, M.; Dominguez, Angélica; Villarroel del Pino, Luis A.; Eriksson, J. G.; Arnáiz Gómez, Pilar; Barja Y., Salesa; Castillo Valenzuela, Oscar; Farías Jofré, Marcelo
    Background and objectives: we have previously studied the association of prenatal growth with metabolic syndrome (MS) components, including insulin resistance (IR), in about two thousand Chilean low-income urban school-age children (J Devel Orig Health Dis. 2012; 3(4): 237-244). We aim to ascertain with a higher sample size the influence of the above mentioned variables. Methods: retrospective cohort study linking information on MS and IR in school-age, with perinatal records. 3325 children were enrolled in schools in the district of Puente Alto (Santiago, Chile) during 2009-2011. Anthropometry and blood pressure (BP) were assessed. A blood sample for determination of glycemia, insulinemia (quimioluminiscence) and blood lipids was taken; HOMA was calculated and a national standard was applied to select HOMA-IR cases. Cook et al standard was used to define MS. We used Pearson correlation, chi-square test and logistic regression step-by-step. Linear and quadratic associations were tested with Poisson regression. Results: 3290 children had complete information at birth (98.9%) 52.01% women; aged 11.4 + 1 years. The prevalence of MS and IR was 7.26% and 25.47%, respectively. Logistic regression analysis showed an inverse association between birth length (BL), gestational age and birth weight (BW) with most dependent variables studied. However BW showed a direct association with the majority of the dependent variables studied. The waist circumference > 90th percentile, BP > 90th percentile and triglycerides > 110 mg/dl were associated with U-shaped BW, BL and ponderal index, respectively. Conclusions: In this new study we could demonstrate a higher number of U-shaped associations with perinatal variables. New studies with higher sample sizes would permit to show this kind of associations and improve our understanding of the early origins of metabolic diseases.
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    ASSOCIATION OF SUBCLINICAL ATHEROSCLEROSIS WITH DIFFERENT STANDARDS OF THE METABOLIC SYNDROME AND INSULIN RESISTANCE
    (2013) Arnai, P.; Dominguez, Angélica; Barja Y., Salesa; Godoy, I.; Villarroel del Pino, Luis A.; Castillo Valenzuela, Oscar; Farías Jofré, Marcelo; Mardones, Francisco
    Background and objectives: we have previously selected two metabolic syndrome (MS) components blood pressure (BP) and high density lipoprotein cholesterol (HDLC) as associated with carotid intima media thickness (CIMT) a surrogate marker of subclinical atherosclerosis in children (Rev Med Chile 2012; 140: 1268-75). We aimed to ascertain with a higher sample size the influence of the above mentioned variables and three standards defining the MS plus three standards defining insulin resistance (IR). Methods: A cross-sectional study of 447 children 10-14 years old of low socio-economic strata from an urban area of Chile was performed during years 2009-2011. This sample was selected considering the presence of one or more MS component and IR. Anthropometry and BP were assessed. A blood sample for determination of glycaemia, insulinemia (quimioluminiscence) and blood lipids were taken; HOMA was calculated and three standards were applied to select HOMA-IR cases. Three standards to define MS were also used. Medium CIMT was assessed using ultrasonography with automated software. Chi-squared test and stepwise regression were used. Results: Mean age was 11.5 ±1.0 years old; 59% girls; 92.6% pubertal; 72% excess weight. Three standards for MS had prevalence of 24.4% (Cook, 2004), 14.1% (IDF, 2007), 42.9% (De Ferranti, 2004). Three standards for HOMA-IR had the following prevalence: 15.2% (Barja, 2011), 37.4% (Burrows, 2006), 23.0% (De Onis, 2012). Elevated blood pressure and reduced CHDL had significant associations with CIMT ≥ percentile 75. The logistic regression for CIMT ≥ percentile 75 only selected BP ≥ percentile 90 (OR = 2.963) and CHDL < 40 mg/dL (OR = 1.789) Conclusions: None of the various classifications for the MS and the HOMA-IR were selected in the multivariate analysis confirming the previously found influence of increased BP and reduced CHDL on medium CIMT.
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    Ateroesclerosis subclínica y síndrome metabólico en niños
    (2013) Arnáiz Gómez, Pilar; Barja Y., Salesa; Villarroel del Pino, Luis A.; Domínguez, Angélica; Godoy J., Iván; Castillo Valenzuela, Oscar; Farías Jofré, Marcelo Enrique; Mardones, Francisco
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    Calidad de vida en niños y adolescentes con atrofia muscular espinal
    (2020) Vega Vega, Paula; Glisser, C.; Castiglioni, C.; Amezquita García, María Virginia; Quirola Sagredo, Marife Andrea; Barja Y., Salesa
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    Clinical assessment underestimates fat mass and overestimates resting energy expenditure in children with neuromuscular diseases
    (2016) Barja Y., Salesa; Pérez, R.
    Background Nutritional problems are frequent among patients with neuromuscular diseases, who consequently need an adequate evaluation. Objective: to describe nutritional assessment and to estimate and measure body composition and energy requirement in children with neuromuscular diseases. Subjects and methods We performed anthropometry, skinfold measurement and bioelectric impedance analysis (BIA) for estimate and measure, respectively, fat mass (FM). Resting energy expenditure (REE) was estimated by Schofield equations and measured by indirect calorimetry (IC). We compared actual energy intake with post-assessment recommendations. Results We studied 40 patients, 13.6 ± 3.3 years old (Range: 5.8–19.3), 80% boys, diagnosed with Duchenne Muscular Dystrophy (n = 21), other dystrophies (7), Muscular Spinal Atrophy (7), myopathies (3) and others (2). According to body mass index (BMI) 22.5% were well nourished (zBMI −1 to +1), 17.5% overweight (zBMI +1 to +2), 17.5% obese (zBMI ≥ +2), and 42.5% undernourished (zBMI < −1). Estimated FM was 20.2% (3.6–46.3), lower than BIA measurement: 34.2% (9.6–60.5) p < 0.001. Estimated REE was higher than measured REE: 1325 (813–2244) vs. 1202 (900–2100) kcal/day, p = 0.002. Actual energy intake: 1452 (1033–2476) was higher than recommended: 1300 (900–1900) kcal/day, p < 0.001. Conclusion Undernutrition and overweight are prevalent in this group of children with neuromuscular diseases. Clinical assessment underestimates FM and overestimates REE.Background Nutritional problems are frequent among patients with neuromuscular diseases, who consequently need an adequate evaluation. Objective: to describe nutritional assessment and to estimate and measure body composition and energy requirement in children with neuromuscular diseases. Subjects and methods We performed anthropometry, skinfold measurement and bioelectric impedance analysis (BIA) for estimate and measure, respectively, fat mass (FM). Resting energy expenditure (REE) was estimated by Schofield equations and measured by indirect calorimetry (IC). We compared actual energy intake with post-assessment recommendations. Results We studied 40 patients, 13.6 ± 3.3 years old (Range: 5.8–19.3), 80% boys, diagnosed with Duchenne Muscular Dystrophy (n = 21), other dystrophies (7), Muscular Spinal Atrophy (7), myopathies (3) and others (2). According to body mass index (BMI) 22.5% were well nourished (zBMI −1 to +1), 17.5% overweight (zBMI +1 to +2), 17.5% obese (zBMI ≥ +2), and 42.5% undernourished (zBMI < −1). Estimated FM was 20.2% (3.6–46.3), lower than BIA measurement: 34.2% (9.6–60.5) p < 0.001. Estimated REE was higher than measured REE: 1325 (813–2244) vs. 1202 (900–2100) kcal/day, p = 0.002. Actual energy intake: 1452 (1033–2476) was higher than recommended: 1300 (900–1900) kcal/day, p < 0.001. Conclusion Undernutrition and overweight are prevalent in this group of children with neuromuscular diseases. Clinical assessment underestimates FM and overestimates REE.
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    Consequences of short sleep duration on the dietary intake in children: A systematic review and metanalysis
    (2018) Cordova, Francisca V.; Barja Y., Salesa; Brockmann Veloso, Pablo Edmundo
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    Diagnóstico y tratamiento de las dislipidemias en niños y adolescentes : recomendaciones de la Rama de Nutrición de la Sociedad Chilena de Pediatría
    (2014) Barja Y., Salesa; Cordero Bayon, María Luisa; Baeza, C.; Hodgson Bunster, María Isabel
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    Dislipidemias en escolares chilenos: prevalencia y factores asociados
    (2015) Barja Y., Salesa; Arnáiz Gómez, Pilar; Villarroel del Pino, Luis A.; Domínguez de Landa, María Angélica; Castillo Valenzuela, Oscar; Farías Jofré, Marcelo Enrique; Mardones S., Francisco
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    Efectos cognitivos de la estimulación audiovisual en niños con limitaciones severa de la movilidad: La utilidad de las tecnologías de apoyo de bajo costo
    (2015) Riveros Miranda, Rodrigo Andrés; Barja Y., Salesa; Muñoz, Carolina; Cancino, Natalia; Nuñez Farías, Alicia Carolina; Ubilla Sanz, Mario; Sylleros, Rodrigo; Olguín, Polín; Rosas Díaz, Ricardo
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    Estado de vitamina D en pacientes con hospitalización prolongada por enfermedades respiratorias crónicas
    (Soc. Chilena Pediatría, 2023) Riutort Kreft, Maria Cecilia; Muñoz Massardo, Eduardo Washington; Bustos-Arriagada, Edson; Munoz, A. Carolina; Barja Y., Salesa
    Los niños con enfermedades respiratorias crónicas (ERC) tienen alto riesgo de deficiencia de vitamina D, la cual puede agravarse en aquellos hospitalizados de forma prolongada, grupo en que se desconoce su prevalencia. Objetivo: determinar el estado de vitamina D en niños con ERC hospitalizados de forma prolongada y explorar factores de riesgo. Pacientes y Método: Estudio transversal realizado en niños con ERC del Hospital Josefina Martínez, presentes entre septiembre y diciembre de 2012. Se registraron datos demográficos, tiempo de hospitalización, antropometría, exposición solar, suplementación y aporte dietario de vitamina D. Se midió 25-Hidroxivitamina D (25(OH)D) en ng/mL, y se definió: suficiencia (> 30), insuficiencia (20 a 30) y deficiencia (< 20). Resultados: Se estudiaron 41 pacientes, 56,1% hombres, con edad mediana de 31 meses (rango: 5 a 146). 51,2% tenía además enfermedad neurológica, 61% eutróficos y 58,5% sin exposición solar. 90,2% recibía suplementación de vitamina D: 65,8% con 400 y 24,4% con 800 UI/día. La concentración promedio de 25(OH)D fue 31,02 ± 6,82 ng/mL. 61% tenía suficiencia, 34,1% insuficiencia y 4,9% deficiencia de vitamina D. Los pacientes que recibían 800 UI/día de Vitamina D tuvieron mayor 25(OH)D que aquellos con menor dosis (p = 0,032), sin existir asociación entre 25(OH)D y sexo, edad, estado nutricional, función motora, exposición solar, uso de anticonvulsivantes ni tiempo de hospitalización. Conclusión: Esta muestra de niños con ERC y hospitalización prolongada presentó alta frecuencia de estado sub-óptimo de vitamina D a pesar de recibir suplementación preventiva, lo cual justifica su adecuada monitorización y dosificación.
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    Estado nutricional, síndrome metabólico y resistencia a la insulina en niños de Santiago, Chile
    (2013) Mardones S., Francisco; Barja Y., Salesa; Arnáiz Gómez, Pilar
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    Estimulación audiovisual en niños con limitación grave de la motricidad
    (2013) Barja Y., Salesa; Muñoz, Carolina; Cancino, Natalia; Nuñez Farías, Alicia Carolina; Ubilla Sanz, Mario; Sylleros, Rodrigo; Rosas Díaz, Ricardo
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    Estimulación audiovisual en niños con limitación grave de la motricidad : ¿mejora su calidad de vida?
    (2013) Barja Y., Salesa; Muñoz Aravena, Carolina del Pilar; Cancino, Natalia; Nuñez Farías, Alicia Carolina; Ubilla Sanz, Mario; Sylleros Ellmen, Álvaro; Riveros Miranda, Rodrigo Andrés; Rosas Díaz, Ricardo
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    Fructose consumption reduces hippocampal synaptic plasticity underlying cognitive performance
    (2015) Cisternas, Pedro; Salazar, Paulina; Serrano, Felipe G.; Montecinos Oliva, Carla; Arredondo, Sebastián B.; Varela Nallar, Lorena Patricia; Barja Y., Salesa; Vio Lagos, Carlos P.; Gomez Pinilla, Fernando; Inestrosa Cantín, Nibaldo
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    Growth and pulmonary function in Chilean children and adolescents with cystic fibrosis
    (2011) Barja Y., Salesa; Espinosa, Tatiana; Cerda Lorca, Jaime Rodrigo; Sánchez Díaz, Ignacio
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    Influence of Feeding Practices on Malnutrition in Haitian Infants and Young Children
    (2018) Irarrazaval, B.; Barja Y., Salesa; Bustos Arriagada, Edson; Doirsaint, R.; Senethmm, G.; Guzman, M.P.; Uauy, Ricardo
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    Is Alzheimer's disease related to metabolic syndrome? A Wnt signaling conundrum
    (2014) Ríos Leal, Juvenal Antonio; Arrese Jiménez, Marco; Barja Y., Salesa; Inestrosa Cantín, Nibaldo