Browsing by Author "Arellano, M."

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    Association between pelvic floor disorder symptoms and QoL scores with depressive symptoms among pelvic organ prolapse patients
    (2016) Gorodischer, A.; Flores Espinoza, Claudia; Goldman, H.; Pizarro Berdichevsky, Javier Alejandro; Hitschfeld, M.; Pattillo Garnham, Alejandro; Blumel, B.; González Bombardiere, Sergio; Arellano, M.; Cuevas Gallegos, Rodrigo; Alvo, J.
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    Incidence and prevalence of hepatitis C virus infection in Chile.
    (2005) González, R.; Soza, A.; Hernández, V.; Pérez, R.M.; Alvarez, M.; Morales, A.; Arellano, M.; Riquelme, A.; Viviani, P.; Covarrubias, C.; Arrese, M.; Miquel, J.F.; Nervi, F.
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    Pro- and anti-inflammatory balance of septic patients is associated with severity and outcome
    (2007) Dougnac Labatut, Alberto; Castro López, Ricardo; Riquelme, Arnoldo; Calvo, M.; Eugenin, E.; Arellano, M.; Pattillo, A.; Regueira Heskia, Tomás; Mercado Flores, Marcelo Esteban; Andresen Hernández, Max Alfonso
    Purpose: To study infl ammatory profi le in patients with sepsis, severe sepsis and septic shock with regards to organ dysfunction and outcome, and to identify a pattern associated with more catastrophic course of illness, organ failure and risk of death. Material and methods: Twenty-nine consecutive patients with sepsis admitted to a medical Intensive Care Unit of a tertiary university hospital (November 2002-December 2003). Plasmatic levels of interleukin-6 (IL-6) and interleukin-10 (IL10) as pro-infl ammatory and anti-infl ammatory markers were measured at baseline, 12, 24 and 48 hours of evolution. Results: There is a positive association between higher levels of IL-6 and severity of the septic process, organ dysfunctions and risk of death, statistically signifi cant at anytime (at baseline, 12, 24 and 48 hours, p <0.05). Higher IL-6/IL-10 ratios associate signifi cantly with risk of death at 24 hours (RR=1.45 if higher or equal to the median). Conclusions: Plasmatic biomarkers measurement during the initial phase of sepsis may help to individualize therapy. An evaluation at 24 h based on IL-6/IL-10 ratio may anticipate a more aggressive infl ammatory profi le. These patients would specially benefi t from immunomodulating therapies to improve survival.