Browsing by Author "Altermatt Couratier, Fernando Rene"
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- ItemAsystole With Propofol and Remifentanil(2001) Muñoz Letelier, Hernán Rodrigo; Altermatt Couratier, Fernando Rene
- ItemComparison of Plasma Concentrations of Levobupivacaine With and Without Epinephrine for Transversus Abdominis Plane Block(2012) Corvetto Aqueveque, Marcia Antonia; Echevarria, Ghislaine C.; Fuente Lopez , Natalia Francisca de la; Mosqueira Podesta, Loreto Alejandra; Solari Gajardo, Sandra; Altermatt Couratier, Fernando Rene"Background and Objectives: The pharmacokinetics for levobupivacaine in transversus abdominis plane (TAP) blocks has not been previously reported. We aimed to determine the extent of the block and the effect on plasma concentrations of levobupivacaine with the addition of epinephrine.", "Methods: We enrolled 11 healthy volunteers in this double-blind, 2-intervention, 2-period crossover study. The intervention periods were defined as a unilateral left TAP block with 20 mL of 0.25% levobupivacaine with (E) or without (no E) 5 mu g/mL epinephrine. Subjects were randomized to E, followed by no E or no E followed by E, with 2-week washout period. Sensory dermatomal anesthesia was recorded. Blood samples were obtained for the measurement of plasma levobupivacaine levels.", "Results: The median cranial-to-caudal spread of sensory blockade for sharp touch was T9 (interquartile range [IQR], T7-T10) to L1 (IQR, T12-L1) with epinephrine and T9 (IQR, T8-T10) to T12 (IQR, T11-L1) without epinephrine (P > 0.05). The mean maximum arterial levobupivacaine concentrations with epinephrine were 0.36 (95% bootstrap confidence interval [95% CI], 0.30-0.42) mu g/mL and 0.63 (95% CI, 0.49-0.85) mu g/mL without epinephrine (P = 0.014, difference in means of 0.27 [95% CI, 0.12-0.46]). The mean maximal venous levobupivacaine concentration was 0.32 (95% CI, 0.28-0.39) mu g/mL and 0.49 (95% CI, 0.37-0.68) mu g/mL, with and without epinephrine, respectively (P = 0.006, difference in means of 0.17 [95% CI, 0.08-0.33]). The mean duration of the blockade was 10.2 hours (95% CI, 8.5-12.5 hours) with epinephrine and 10.3 hours (95% CI, 8.7-12.4 hours) without epinephrine (P = 1.000).", "Conclusions: Adding epinephrine to levobupivacaine reduces its peak plasma concentration after unilateral TAP blocks, with no remarkable effects on block characteristics or duration."]
- ItemComparison of the effectiveness of peripheral nerve blockers made with neurostimulator versus ultrasound: Systematic review and meta-analysis(2008) Cabrera Viera, Francisca; Torres Perez, David; Altermatt Couratier, Fernando Rene
- ItemHealth Care Simulation as a Training Tool for Epidemic Management: A Systematic Review(2023) Corvetto Aqueveque, Marcia Antonia; Altermatt Couratier, Fernando Rene; Belmar Riveros, Francisca Andrea; Escudero Zuniga, Eliana XimenaThe objective of this research was to identify and review studies that have evaluated the impact of simulation-based training on health care professionals during epidemics.All studies in health care simulation-based training published during the last 5 epidemics with a global impact (SARS-CoV, H1N1, MERS, Ebola, SARS-CoV-2; through July 2021) were selected from a systematic search of PUBMED, EMBASE, and key journals.The search strategy identified 274 studies; 148 met the inclusion criteria and were included. Most of the studies were developed in response to SARS-CoV-2 infection (n = 117, 79.1%), used a descriptive approach (n = 54, 36.5%), and were used to train technical skills (n = 82, 55.4%).This review demonstrates a growing interest in publications related to health care simulation and epidemics. Most of the literature is marked by limited study designs and outcome measurements, although there is a trend toward the use of more refined methodologies in the most recent publications. Further research should seek the best evidence-based instructional strategies to design training programs in preparation for future outbreaks.
- ItemImpact of peripheral regional anesthesia in ambulatory surgery(2011) Quiroga Bravo, Camila Andrea; Altermatt Couratier, Fernando Rene
- ItemMixing and using dantrolene for simulated malignant hyperthermia crisis(2012) Corvetto Aqueveque, Marcia Antonia; Montana Rodriguez, Rodrigo Alejandro; Bravo Bertoglio, Maria Pia; Altermatt Couratier, Fernando Rene
- ItemResearch priorities in regional anaesthesia: an international Delphi study(2024) Ferry, Jenny; Lewis, Owen; Lloyd, James; El-Boghdadly, Kariem; Kearns, Rachel; Albrecht, Eric; Altermatt Couratier, Fernando Rene; Ashokka, Balakrishnan; Ayad, Amany E.; Aziz, Ezzat S.; Aziz, Lutful A; Jagannathan, Balavenkatasubramanian; Bouarroudj, Noreddine; Chin, Ki Jinn; Delbos, Alain; Gracia, Alex de; Ip, Vivian H. Y.; Kwofie, Kwesi; Layera, Sebastián; Lobo, Clara A.Background: Regional anaesthesia use is growing worldwide, and there is an increasing emphasis on research in regional anaesthesia to improve patient outcomes. However, priorities for future study remain unclear. We therefore conducted an international research prioritisation exercise, setting the agenda for future investigators and funding bodies. Methods: We invited members of specialist regional anaesthesia societies from six continents to propose research questions that they felt were unanswered. These were consolidated into representative indicative questions, and a literature review was undertaken to determine if any indicative questions were already answered by published work. Unanswered indicative questions entered a three-round modified Delphi process, whereby 29 experts in regional anaesthesia (representing all participating specialist societies) rated each indicative question for inclusion on a final high priority shortlist. If ≥75% of participants rated an indicative question as ‘definitely’ include in any round, it was accepted. Indicative questions rated as ‘definitely’ or ‘probably’ by <50% of participants in any round were excluded. Retained indicative questions were further ranked based on the rating score in the final Delphi round. The final research priorities were ratified by the Delphi expert group. Results: There were 1318 responses from 516 people in the initial survey, from which 71 indicative questions were formed, of which 68 entered the modified Delphi process. Eleven ‘highest priority’ research questions were short listed, covering themes of pain management; training and assessment; clinical practice and efficacy; technology and equipment. Conclusions: We prioritised unanswered research questions in regional anaesthesia. These will inform a coordinated global research strategy for regional anaesthesia and direct investigators to address high-priority areas.