Comparison of isoflurane, halothane and fentanyl in patients with decreased ejection fraction undergoing coronary surgery
link https://doi.org/10.1177/0310057X9602400513account_box Urzua, Jaccount_box Serra, Maccount_box Lema, Gaccount_box Canessa, Raccount_box Gonzalez, Raccount_box Meneses, Gaccount_box Irarrazaval, Maccount_box Moran, S
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The aim of the study was to compare three anaesthetic agents in patients with ejection fraction below 0.40 subjected to coronary revascularization surgery. Twenty-five elective coronary surgical patients with ejection fraction below 0.40 were prospectively studied. Premedication was pethidine 1 mg/kg and induction was fentanyl 0.03 mg/kg and pancuronium 0.1 mg/kg. The patients were randomized to one of three maintenance techniques (fentanyl, isoflurane or halothane).
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| Autor | Urzua, J Serra, M Lema, G Canessa, R Gonzalez, R Meneses, G Irarrazaval, M Moran, S |
| Título | Comparison of isoflurane, halothane and fentanyl in patients with decreased ejection fraction undergoing coronary surgery |
| Revista | ANAESTHESIA AND INTENSIVE CARE |
| ISSN | 0310-057X |
| Volumen | 24 |
| Número de publicación | 5 |
| Página inicio | 579 |
| Página final | 584 |
| Fecha de publicación | 1996 |
| Resumen | The aim of the study was to compare three anaesthetic agents in patients with ejection fraction below 0.40 subjected to coronary revascularization surgery. Twenty-five elective coronary surgical patients with ejection fraction below 0.40 were prospectively studied. Premedication was pethidine 1 mg/kg and induction was fentanyl 0.03 mg/kg and pancuronium 0.1 mg/kg. The patients were randomized to one of three maintenance techniques (fentanyl, isoflurane or halothane). Radial arterial pressure, heart rate, right atrial pressure, pulmonary arterial and occluded pressures, and thermo-dilution cardiac output were measured, and cardiac inner and resistance calculated, at the following times: before induction; 5 min after intubation; 2 min after sternotomy; immediately after discontinuation of bypass, 15 min afterwards; immediately after sternal closure; during suture of the skin; 5 min after arrival in the postoperative care unit; and 60 min postoperatively. Mean arterial pressure decreased significantly in the isoflurane group and nonsignificantly in the halothane group after induction. Cardiac index decreased significantly in the isoflurane group and nonsignificantly in the halothane group after induction and after sternotomy. Neither pressure nor flow decreased in patients receiving fentanyl. Following weaning from cardiopulmonary bypass, systemic vascular resistance decreased significantly in all groups. Cardiac index, however did not increase above control values and arterial pressure consequently decreased; there was no significant difference between groups. |
| Derechos | registro bibliográfico |
| DOI | 10.1177/0310057X9602400513 |
| Editorial | AUSTRALIAN SOC ANAESTHETISTS |
| Enlace | |
| Id de publicación en Pubmed | MEDLINE:8909670 |
| Id de publicación en WoS | WOS:A1996VN21600012 |
| Paginación | 6 páginas |
| Palabra clave | surgery coronary anaesthetics, volatile halothane isoflurane anaesthetics, intravenous fentanyl CHRONICALLY INSTRUMENTED DOG ARTERY BYPASS-SURGERY INTRAOPERATIVE HYPERTENSION BLOOD-FLOW CARDIOPULMONARY BYPASS VOLATILE ANESTHETICS DESFLURANE ENFLURANE DISEASE CONTRACTILITY |
| Tipo de documento | artículo |