Ligation of left anterior descending coronary artery. Surgical technique
link http://dx.doi.org/10.4067/S0718-40262012000100003get_appLigation of left anterior descending coronary artery. Surgical technique.pdf
account_box Olivares R., Gabrielaccount_box Moran V., Sergioaccount_box Palacios M., Cristianaccount_box Apablaza E., Felipeaccount_box Godoy J., Ivanaccount_box Zalaquett S., Ricardoaccount_box Paz Ocaranza J., Maria
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Ligation of left anterior descending coronary artery. Surgical technique
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| Autor | Olivares R., Gabriel Moran V., Sergio Palacios M., Cristian Apablaza E., Felipe Godoy J., Ivan Zalaquett S., Ricardo Paz Ocaranza J., Maria |
| Título | Ligation of left anterior descending coronary artery. Surgical technique |
| Revista | REVISTA CHILENA DE CIRUGIA |
| ISSN | 0379-3893 |
| Volumen | 64 |
| Número de publicación | 1 |
| Página inicio | 15 |
| Página final | 18 |
| Fecha de publicación | 2012 |
| Resumen | Ligation of left anterior descending coronary artery. Surgical technique Background: An experimental model for ligation of the left anterior descending coronary artery (ADA) in rats has been commonly used in research into ischemic cardiopathy. However, this procedure is very difficult, with a high mortality rate. There is little information in the literature regarding its technical aspects. Our objective was to describe a surgical technique for ADA ligation in rats. Material and Method: Fifty-one Sprague-Dawley male rats weighting 230 +/- 20 gr were anaesthetized and connected to mechanical ventilation. Through a left-side thoracothomy we ligated the ADA 2 mm below the junction of the pulmonary artery and the left atrial appendage. The next day we performed transthoracic echocardiography to confirm our results. Results: The mortality rate was 7.8% (4 out of 51). The main cause of death was hemorrhage during surgery. The average time for the procedure was 45 +/- 5 min. We confirmed hypokinesia of the anterior lateral wall in 100% of the surviving rats. Discussion: This procedure was reproducible and safe, with less than 10% mortality. |
| Derechos | acceso abierto |
| Editorial | SOC CIRUJANOS CHILE |
| Enlace | |
| Id de publicación en WoS | WOS:000299365600003 |
| Paginación | 4 páginas |
| Palabra clave | Ligation coronary vessels rats animal experimentation heart surgical procedure MYOCARDIAL-INFARCTION RAT |
| Tema ODS | 03 Good Health and Well-being |
| Tema ODS español | 03 Salud y bienestar |
| Tipo de documento | artículo |