Background: Cardiovascular risk factors must be controlled since childhood. Aim: To assess the association of carotid intima media thickness (CIMT) with the components of the metabolic syndrome in Children. Material and Methods: Cross sectional assessment of 299 children aged 11.5 +/- 0.9 years (58% women) with and without metabolic syndrome components. Anthropometric parameters and blood pressure were measured and a blood sample was obtained to measure blood glucose and lipids. CIMT was measured using high resolution ultrasound. Results: Ninety three percent of children were post puberal, 64% were overweight and 25% had metabolic syndrome. Mean and maximum CIMT correlated with systolic blood pressure (r = 0.21 and 0.21 respectively p < 0.01). Children with a CIMT over the 75th percentile had higher blood pressure and lower HDL cholesterol. A stepwise logistic regression accepted both variables as predictors of CIMT with odds ratios for mean CIMT of 1.46 (1.19-1-79) and 0.81 (0.7-0.94) per five units of change, respectively. Conclusions: In this group of children systolic blood pressure and HDL cholesterol are associated to CIMT. (Rev Med Chile 2012; 140: 1268-1275).
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Autor | Arnaiz, Pilar Villarroel, Luis Barja, Salesa Godoy, Ivan Cassis, Berta Dominguez, Angelica Castillo, Oscar Farias, Marcelo Carvajal, Jacqueline Cristina Tinoco, Ana Mardones, Francisco |
Título | Association of carotid intima media thickness with blood pressure and HDL cholesterol in children |
Revista | REVISTA MEDICA DE CHILE |
ISSN | 0034-9887 |
ISSN electrónico | 0717-6163 |
Volumen | 140 |
Número de publicación | 10 |
Página inicio | 1268 |
Página final | 1275 |
Fecha de publicación | 2012 |
Resumen | Background: Cardiovascular risk factors must be controlled since childhood. Aim: To assess the association of carotid intima media thickness (CIMT) with the components of the metabolic syndrome in Children. Material and Methods: Cross sectional assessment of 299 children aged 11.5 +/- 0.9 years (58% women) with and without metabolic syndrome components. Anthropometric parameters and blood pressure were measured and a blood sample was obtained to measure blood glucose and lipids. CIMT was measured using high resolution ultrasound. Results: Ninety three percent of children were post puberal, 64% were overweight and 25% had metabolic syndrome. Mean and maximum CIMT correlated with systolic blood pressure (r = 0.21 and 0.21 respectively p < 0.01). Children with a CIMT over the 75th percentile had higher blood pressure and lower HDL cholesterol. A stepwise logistic regression accepted both variables as predictors of CIMT with odds ratios for mean CIMT of 1.46 (1.19-1-79) and 0.81 (0.7-0.94) per five units of change, respectively. Conclusions: In this group of children systolic blood pressure and HDL cholesterol are associated to CIMT. (Rev Med Chile 2012; 140: 1268-1275). |
Derechos | acceso abierto |
DOI | 10.4067/S0034-98872012001000005 |
Editorial | SOC MEDICA SANTIAGO |
Enlace | |
Id de publicación en Pubmed | MEDLINE:23559283 |
Id de publicación en WoS | WOS:000311884500005 |
Paginación | 8 páginas |
Palabra clave | Blood pressure Carotid Intima-Media thickness Child Cholesterol HDL CARDIOVASCULAR RISK-FACTORS METABOLIC SYNDROME CHILDHOOD OBESITY ABDOMINAL OBESITY ADULT HEALTH YOUNG FINNS INSULIN ADOLESCENTS ATHEROSCLEROSIS DETERMINANTS |
Tema ODS | 03 Good Health and Well-being |
Tema ODS español | 03 Salud y bienestar |
Tipo de documento | artículo |