2-Methoxyestradiol (2ME) is an endogenous metabolite of 17β-estradiol with antiangiogenic and antitumor properties, although its mechanisms of action remain unclear. Progestins in hormone replacement therapy increase the risk of breast cancer. Progesteron
Registro Sencillo
Registro Completo
Autor | Quezada, M. Diaz, J. Henriquez, S. Bravo Castillo, María Loreto Aranda, E. Oliva, B. Villalón, Manuel J. Kato Cardemil, Sumie Rode Cuello F., Mauricio Brosens, J. J. Lange, C. A. Owen, Gareth Ivor |
Título | 2-Methoxyestradiol inhibits progesterone-dependent tissue factor expression and activity in breast cancer cells |
Revista | Hormones and Cancer |
Volumen | Vol. 1 |
Número de publicación | No. 3 |
Página inicio | 117 |
Página final | 126 |
Fecha de publicación | 2010 |
Resumen | 2-Methoxyestradiol (2ME) is an endogenous metabolite of 17β-estradiol with antiangiogenic and antitumor properties, although its mechanisms of action remain unclear. Progestins in hormone replacement therapy increase the risk of breast cancer. Progesteron |
Derechos | acceso abierto |
DOI | 10.1007/s12672-010-0019-5 |
Enlace | |
Paginación | 10 páginas |
Palabra clave | 2-Methoxyestradiol Breast cancer Progesterone receptor STAT5 Tissue factor |
Temática | Medicina y salud |
Tipo de documento | artículo |